Now showing items 111-119 of 119
The North American Multiple System Atrophy Study Group
(Springer-Verlag; Springer-Verlag/Wien, 2005-12)
The North American Multiple System Atrophy Study Group involves investigators in 12 US medical centers funded by a grant from the National Institutes of Health. The objectives are to examine the environmental and genetic ...
Transplantation of hNT neurons into the ischemic cortex: Cell survival and effect on sensorimotor behavior
(Wiley Subscription Services, Inc., A Wiley Company, 2006-05-01)
Cell transplantation offers a potential new treatment for stroke. Animal studies using models that produce ischemic damage in both the striatum and the frontal cortex have shown beneficial effects when hNT cells (postmitotic ...
Post‐training stimulation of the right dorsolateral prefrontal cortex impairs working memory training performance
(Wiley Periodicals, Inc.Academic Press, 2021-10)
Research investigating transcranial direct current stimulation (tDCS) to enhance cognitive training augments both our understanding of its long‐term effects on cognitive plasticity as well as potential applications to ...
Investigation of Apoptosis and Metabolism as Mechanisms of Trichloroethylene Toxicity During Pregnancy
(2020)
Trichloroethylene (TCE), an organic solvent with multiple industrial uses, is associated with adverse pregnancy outcomes in epidemiological studies. In timed-pregnant Wistar rats, TCE exposure reduces fetal weight. ...
Inside or Out: Characterizing petrobactin use by Bacillus anthracis
(2018)
Bacillus anthracis is a Gram-positive, spore-forming bacillus and causes the disease anthrax. Anthrax is a deadly infection that begins with phagocytosis of a B. anthracis spore by an antigen presenting cell and ends when ...
The Road to Identifying Disease Causing Genes: Association Tests, Genotype Imputations, and Sampling Strategies for Sequencing Studies.
(2013)
Technological advances now allow investigators to use sequencing data to identify genetic risk variants for complex diseases. However, it is still expensive to sequence a large sample of individuals. While genotype imputation ...
Spatial and Temporal Protein Oxidation and Redox Signaling in Mechanisms of Structural Birth Defects
(2021)
Neural tube defects (NTDs) are birth defects that arise from failed neural tube closure resulting in morphological abnormality of the brain and spinal cord. NTD risk has been associated with genetic mutations, a maternal ...
Hsp70 chaperone Proteins and their Interactions with Various Drugs as Studied by Nuclear Magnetic Resonance.
(2011)
Chaperone proteins and their cochaperones are perhaps one of the most intriguing systems for investigation. Ubiquitous in nature, they can be found in every organism and that perhaps is the reason that their sequence shows ...
Mimicking partial to total placental insufficiency in a rabbit model of cerebral palsy
(Springer International PublishingWiley Periodicals, Inc., 2022-12)
All placental abruptions begin as partial abruptions, which sometimes manifest as fetal bradycardia. The progression from partial to total abruption was mimicked by a new rabbit model of placental insufficiency, and we ...