Now showing items 6631-6640 of 6643
Relationships of Diet Quality, Sedentary Behavior, and DNA Methylation Patterns with Cardiometabolic Risk Factors among Children and Adolescents
(2021)
Among youth, there has been a parallel increase in the prevalence of obesity and cardiometabolic abnormalities, including central obesity, glucose intolerance, elevated blood pressure, and dyslipidemia. This cluster of ...
Prevention Strategies for Gynecologic Cancers
(2022)
This dissertation focused on prevention strategies for ovarian and cervical cancers. Primary prevention of ovarian cancer was explored in Aim 1 using data from the Ovarian Cancer Association Consortium (OCAC; 7,743 cases; ...
Dynamics of Influenza Protection and Infection: Implications for Vaccination Development
(2022)
Influenza is a major contributor to respiratory morbidity and mortality worldwide and is a particular concern for high-risk populations including children. Although influenza has been studied for over 100 years, major gaps ...
Body composition and mortality in men receiving prostate radiotherapy: A pooled analysis of NRG/RTOG 9406 and NRG/RTOG 0126
(Wiley Periodicals, Inc., 2023-03-01)
PurposeTo validate the association between body composition and mortality in men treated with radiation for localized prostate cancer (PCa). Secondarily, to integrate body composition as a factor to classify patients by ...
CCNE1 and survival of patients with tubo-ovarian high-grade serous carcinoma: An Ovarian Tumor Tissue Analysis consortium study
(Wiley Periodicals, Inc., 2023-03-01)
BackgroundCyclin E1 (CCNE1) is a potential predictive marker and therapeutic target in tubo-ovarian high-grade serous carcinoma (HGSC). Smaller studies have revealed unfavorable associations for CCNE1 amplification and ...
Associations between PFAS perceptions and consumer behaviors across Michigan
(2024-03-26)
Per- and polyfluoroalkyl substances (PFAS) have been associated with various adverse health effects. Few studies, however, have explored public perceptions, which may influence behaviors related to PFAS exposure. We ...
Development and Validation of Transportable, Clinically Applicable and Scalable Machine Learning Models for Acute Kidney Injury
(2024)
Acute kidney injury (AKI), a frequent complication in hospitalized patients, poses significant challenges due to its high incidence, short-term mortality, and substantial economic burden. Current AKI models utilizing ...
Critical Race Approaches to Understanding Health Inequities Impacting Trans People of Color in the United States
(2024)
This dissertation critically examines structural drivers of health inequities impacting trans people of color in the United States. To do so, I use theories that concern how the structural power dynamics that drive these ...
The Public Health Consequences of Compounding Disasters and Colonialism in Puerto Rico: A Mixed-Methods Investigation
(2024)
In recent decades, the ongoing climate crisis has disproportionately impacted historically marginalized populations globally through environmental hazards and disasters. Understanding the health impacts of multiple disaster ...
Bayesian Methods for snSMART Designs with External Controls and Dynamic Prediction of Landmark Survival Time in Cancer Clinical Trials
(2024)
In Duchenne muscular dystrophy (DMD) and other rare diseases, recruiting patients into clinical trials is challenging. Additionally, assigning patients to long-term, multi-year placebo arms raises ethical and trial retention ...