Now showing items 31-40 of 463
Benzimidazole ribonucleosides: Observation of an unexpected nitration when performing non-aqueous diazotizations with t-butyl nitrite
(Elsevier, 1992-09)
Mild, non-acidic conditions used in the non-aqueous diazotization of a 2-aminobenzimidazole nucleoside with t-butyl nitrite gave an unexpected 4-nitrobenzimidazol-2-one nucleoside which was not formed when primary alkyl ...
Triple Junction Mobility: A Molecular Dynamics Study
(Kluwer Academic Publishers; Springer Science+Business Media, 1999-11)
We present a molecular dynamics simulation study of the migration of individual grain boundary triple junctions. The simulation cell was designed to achieve steady state migration. Observations of the triple junction angle ...
Thermodynamics of alkali alkanoates IX. Heat capacity and thermodynamic functions of lithium 2-methylpropanoate at temperatures from 7 K to 535 K
(Elsevier, 1993-10)
The heat capacity of lithium 2-methylpropanoate was measured by equilibrium adiabatic calorimetry at temperatures, T from 7 K up to 350 K and by d.s.c. from 330 K through melting to 535 K. A small diffuse hump was observed ...
Effects of neuropeptide Y, insulin, 2-deoxyglucose, and food deprivation on food-motivated behavior
(Springer-Verlag, 1995-08)
The current study demonstrates the ability of neuropeptide Y (NPY) to increase break points under a progressive ratio 1 (PR1) reinforcement schedule. An initial response resulted in delivery of a food reinforcer (45 mg ...
Selective multiple methylene insertion reactions mediated by iodomethylzine iodide: Mechanistic considerations and synthetic applications
(Elsevier, 1991-04-15)
The reaction of alkynylcoppers 1 with an excess of iodomethylzinc iodide selectively furnishes the quadruple methylene insertion copper organometallics 2 in fair to good yields. The mechanism of the reaction has been ...
Polyhedral liquid crystal silsesquioxanes
(John Wiley & Sons, Ltd., 1999-04)
Synthetic routes towards monodisperse polyhedral liquid-crystalline silsesquioxanes are described. The liquid-crystalline phase behaviour of these structurally uniform materials, with various silsesquioxane core and mesogenic ...
Glucocorticoid-reinforced responding in the rhesus monkey
(Springer-Verlag; Springer-Verlag Berlin Heidelberg, 1999-11)
Rationale: Glucocorticoids have been reported to have rewarding effects in rats and may lead to drug-seeking behavior in humans under some circumstances. Objectives: The present study investigated whether glucocorticoids ...
New vectors for high level expression of recombinant proteins in bacteria
(Elsevier, 1992-05-01)
A system has been developed for synthesis and rapid purification of recombinant polypeptides expressed in frame with glutathione S-transferase ([3.], Gene 67, 31-40). Expressed fusion proteins are purified from bacterial ...
Fluorescence Yield Near Edge Spectroscopy (FYNES) of benzene adsorbed in Na-Y zeolite
(Baltzer Science Publishers, Baarn/Kluwer Academic Publishers; J.C. Baltzer AG, Scientific Publishing Company ; Springer Science+Business Media, 1990-01)
Benzene adsorbed in sodium-Y zeolite has been investigated using Fluorescence Yield Near Edge Spectroscopy (FYNES). These studies demonstrate that FYNES measurements are feasible as a direct probe of the local electronic ...
Mechanism and pharmacological specificity of dUTPase-mediated protection from DNA damage and cytotoxicity in human tumor cells
(Springer-Verlag; Springer-Verlag Berlin Heidelberg, 1998-09)
Purpose : We have reported previously that the expression of E. coli dUTPase (dutE) can protect HT29 cells from 5-fluorodeoxyuridine (FdUrd)-induced DNA fragmentation and cytotoxicity. In the study reported here, we further ...