Now showing items 981-990 of 992
Specific steroid response from a nonspecific DNA element
(Elsevier, 1994-06)
A fundamental dilemma of steroid hormone regulation is how specific transcription is attained in vivo when several receptors recognize the same DNA sequence in vitro. We have identified an enhancer of the mouse sex-limited ...
Dinucleotide polymorphism at the DXS1178 locus is tightly linked to PGK1 at Xq13
(Springer-Verlag, 1995-04)
A polymorphic CA repeat (locus name DXS1178 ) was isolated from a 1-megabase YAC (OTCC) containing the OTC gene, located at Xp21.1. However, amplification in human-rodent hybrid cells and segregation analysis in three CEPH ...
Enzymatic synthesis of sialyl Lex and derivatives based on a recombinant fucosyltransferase
(Elsevier, 1991)
A recombinant human Lewis [alpha](1,3/1,4)fucosyltranferase has been studied for its acceptor substrate specificity and used in the synthesis of sialyl Lex and derivatives.
Mass transfer effects on microbial uptake of naphthalene from complex NAPLs
(Wiley Subscription Services, Inc., A Wiley Company, 1998-12-20)
The bioavailability of naphthalene present as a component of a complex nonaqueous phase liquid (NAPL) comprised by nine aromatic compounds was investigated. Specifically, the effects of naphthalene mass transfer from the ...
Effect of fixation temperature on flow cytometric measurement of intracellular antibody content of hybridomas during batch culture
(Kluwer Academic Publishers; Science & Technology Letters ; Springer Science+Business Media, 1993-04)
In order to investigate the effect of fixation temperature on flow cytometric measurement of intracellular antibody content of hybridoma cells, cells in different growth stages during a batch culture were fixed and stored ...
Adrenal proteins bound by a reactive intermediate of mitotane
(Springer-Verlag; Springer-Verlag Berlin Heidelberg, 1997-02)
Purpose : Mitotane ( o,p ′-DDD), is the only adrenolytic agent available for the treatment of adrenocortical carcinoma. Previous studies have shown that mitotane covalently binds to adrenal proteins following its metabolism ...
Sites of synthesis of chromogranins A and B in the human brain
(Elsevier, 1992-04)
The sites of synthesis of the chromogranins A and B, and their potential processed peptides, were examined by quantitating the levels of chromogranin A and B mRNA in various regions of the human brain by Northern blot ...
Naltrexone reduces ethanol- and sucrose-reinforced responding in rhesus monkeys
(Springer-Verlag; Springer-Verlag Berlin Heidelberg, 1998-09)
These experiments evaluated the ability of naltrexone (NTX) to reduce selectively oral and IV ethanol-reinforced responding, and examined the ethanol-NTX interaction in terms of the competitive opioid antagonist property ...
cDNA sequence and genomic structure of EVI2B, a gene lying within an intron of the neurofibromatosis type 1 gene
(Elsevier, 1991-03)
The gene responsible for neurofibromatosis type 1 (NF1), one of the more common inherited human disorders, was identified recently, and segments of it were cloned. Two translocation breakpoints that interrupt the NF1 gene ...
Lipomide dehydrogenase from Azotobacter vinelandii : site-directed mutagenesis of the His450-Glu455 diad
(Blackwell Publishing Ltd, 1992-07)