Now showing items 11-20 of 894
Interrupted aortic arch in a child with trisomy 5q31.1q35.1 due to a maternal (20;5) balanced insertion
(Wiley Subscription Services, Inc., A Wiley Company, 2003-01-30)
Complex congenital heart defects (CHD) are associated with a variety of single gene abnormalities and chromosomal rearrangements. Of the various forms of CHD, aortic arch interruption, a conotruncal heart defect, is ...
Macrophage infiltration in human non-small-cell lung cancer: the role of CC chemokines
(Springer-Verlag; Springer-Verlag Berlin Heidelberg, 2000-04)
Bronchogenic carcinoma is the leading cause of malignancy-related mortality in the United States, with an overall 5-year survival rate of less than 15%. This aggressive behavior reflects, among other traits, the capacity ...
Substituent effects on the oxidation of substituted biphenyl congeners by type II methanotroph strain CSC1
(Springer-Verlag, 2005-05)
The oxidation potential of type II groundwater methanotroph, strain CSC1, expressing soluble methane monooxygenase, was measured in the presence of 10 ortho -substituted biphenyls with varying electronics, sterics, and ...
2-(3-Pyrrolin-1-yl)-1,4-naphthoquinones: Photoactivated Alkylating Agents
(WILEY-VCH Verlag, 2008-09)
The preparation of 2-(3-pyrrolin-1-yl)-1,4-naphthoquinones and a study of their use as photoactivated alkylating agents is reported. The title compounds were easily synthesized by conjugate addition of the corresponding ...
Using sex-averaged genetic maps in multipoint linkage analysis when identity-by-descent status is incompletely known
(Wiley Subscription Services, Inc., A Wiley Company, 2006-07)
The ratio of male and female genetic map distances varies dramatically across the human genome. Despite these sex differences in genetic map distances, most multipoint linkage analyses use sex-averaged genetic maps. We ...
Modeling intra-tumor protein expression heterogeneity in tissue microarray experiments
(John Wiley & Sons, Ltd., 2008-05-20)
Tissue microarrays (TMAs) measure tumor-specific protein expression via high-density immunohistochemical staining assays. They provide a proteomic platform for validating cancer biomarkers emerging from large-scale DNA ...
Differentiation of activated satellite cells in denervated muscle following single fusions in situ and in cell culture
(Springer-Verlag, 2005-07)
Satellite cells represent a cellular source of regeneration in adult skeletal muscle. It remains unclear why a large pool of stem myoblasts in denervated muscle does not compensate for the loss of muscle mass during ...
Engineering Specific Cross‐Links in Nucleic Acids Using Glycol Linkers
(Wiley Periodicals, Inc., 2000-02)
One of the most convenient methods for generating oligonucleotides possessing intra‐ or interstrand cross‐links is through incorporation of oligoethylene glycol bridges by solid‐phase synthesis. The reagents are commercially ...
Proteomics FASTA Archive and Reference Resource
(WILEY-VCH Verlag, 2008-05)
A FASTA file archive and reference resource has been added to ProteomeCommons.org. Motivation for this new functionality derives from two primary sources. The first is the recent FASTA standardization work done by the Human ...
Disrupting Mediator with a Short Peptide Ligand
(WILEY-VCH Verlag, 2007-07-23)
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