Now showing items 401-410 of 410
Introduction to the Synthesis and Purification of Oligonucleotides
(Applied BiosystemsWiley Periodicals, Inc., 2000-02)
Modern nucleic acid synthesizers utilize phosphite triester chemistries that employ stable phosphoramidite monomers to build a growing polymer. These robust reactions allow easy generation of specific oligodeoxyribo‐ and ...
A phase II study of chloroquinoxaline sulfonamide (CQS) in patients with metastatic colorectal carcinoma (MCRC)
(Kluwer Academic Publishers; Springer Science + Business Media, Inc, 2006-01-28)
Purpose: Phase II multicenter study investigated the efficacy and toxicity of the novel halogenated derivative of sulfaquixonaline Chloroquinoxaline Sulfonamide (CQS) in metastatic colorectal cancer. Experimental design: ...
Proteomic analysis of estrogen response of premalignant human breast cells using a 2-D liquid separation/mass mapping technique
(WILEY-VCH Verlag, 2006-07)
A 2-D liquid-phase separation method based on chromatofocusing and nonporous silica RP-HPLC followed by ESI-TOF-MS was used to analyze proteins in whole cell lysates from estrogen-treated and untreated premalignant, ...
Determination of Α-helix and Β-sheet stability in the solid state: A solid-state NMR investigation of poly( L -alanine)
(Wiley Subscription Services, Inc., A Wiley Company, 2002-08-15)
The relative stability of Α-helix and Β-sheet secondary structure in the solid state was investigated using poly( L -alanine) (PLA) as a model system. Protein folding and stability has been well studied in solution, but ...
Atmospheric chemistry of cyclohexanone: UV spectrum and kinetics of reaction with chlorine atoms
(Wiley Subscription Services, Inc., A Wiley Company, 2008-05)
Absolute and relative rate techniques were used to study the reactivity of Cl atoms with cyclohexanone in 6 Torr of argon or 800–950 Torr of N 2 at 295 ± 2 K. The absolute rate experiments gave k (Cl + cyclohexanone) = ...
Physicochemical properties of blue fluorescent protein determined via molecular dynamics simulation
(Wiley Subscription Services, Inc., A Wiley Company, 2008-12)
Blue fluorescent protein (BFP) is a mutant of green fluorescent protein (GFP), where the chromophore has been modified to shift the emitted fluorescence into the blue spectral region. In this study, MD calculations were ...
Kinetics of the gas-phase reactions of chlorine atoms with CH 2 F 2 , CH 3 CCl 3 , and CF 3 CFH 2 over the temperature range 253–553 K
(Wiley Subscription Services, Inc., A Wiley Company, 2009-06)
Relative rate techniques were used to study the title reactions in 930–1200 mbar of N 2 diluent. The reaction rate coefficients measured in the present work are summarized by the expressions k (Cl + CH 2 F 2 ) = 1.19 × ...
Chemometric Methods for the Determination of Volatile Organic Compounds with Microsensor Arrays.
(2008)
This research addresses critical chemometric modeling and data analysis functions needed to guide the design and implementation of novel meso-scale and micro-scale instrumentation that incorporates chromatographic separation ...