Now showing items 61-70 of 177
Development of selected reaction monitoring-MS methodology to measure peptide biomarkers in prostate cancer
(WILEY-VCH Verlag, 2010-10)
Prostate cancer is a leading cause of cancer-related death. The current modality of diagnosis, the measurement of serum PSA, not only suffers from lack of specificity, but does not distinguish clinical cases in which current ...
A NMR Investigation of Structure and Allostery in the Hsp70 Chaperone System.
(2010)
The Hsp70 Chaperone system is a complex molecular machine composed of proteins. It is responsible for assisting in protein folding/refolding/processing and transport. Hsp70 proteins have been historically associated with ...
Functionalized Synthetic Biodegradable Polymer Scaffolds for Tissue Engineering
(WILEY‐VCH Verlag, 2012-07)
Scaffolds (artificial ECMs) play a pivotal role in the process of regenerating tissues in 3D. Biodegradable synthetic polymers are the most widely used scaffolding materials. However, synthetic polymers usually lack the ...
Label‐free profiling of white adipose tissue of rats exhibiting high or low levels of intrinsic exercise capacity
(Wiley Periodicals, Inc., 2015-07)
Front Cover: Glycosylation via Transition‐Metal Catalysis: Challenges and Opportunities (Eur. J. Org. Chem. 28/2016)
(Wiley Periodicals, Inc., 2016-10)
Synthesis of β‐Cyclodextrin Containing Copolymer via “Click” Chemistry and Its Self‐Assembly in the Presence of Guest Compounds
(WILEY‐VCH Verlag, 2012-04-23)
We report the synthesis of a hydrophilic copolymer with one polyethylene glycol (PEG) block and one β‐cyclodextrin (β‐CD) containing block by a “click” reaction between azido‐substituted β‐CD and propargyl flanking copolymer. ...
Carbohydrate‐Based Polymer Brushes Prevent Viral Adsorption on Electrostatically Heterogeneous Interfaces
(Wiley‐Blackwell, 2019-01)
Chemical heterogeneity on biomaterial surfaces can transform its interfacial properties, rendering nanoscale heterogeneity profoundly consequential during bioadhesion. To examine the role played by chemical heterogeneity ...
Effects of Acute and Sustained Pain Manipulations on Performance in a Visual‐Signal Detection Task of Attention in Rats
(ElsevierWiley Periodicals, Inc., 2015-06)
Preclinical ResearchPatients with pain often display cognitive impairment including deficits in attention. The visual‐signal detection task (VSDT) is a behavioral procedure for assessment of attention in rodents. Male ...
Metabolomics revealed the toxicity of cationic liposomes in HepG2 cells using UHPLC‐Q‐TOF/MS and multivariate data analysis
(Wiley Periodicals, Inc., 2017-12)
Cationic liposomes (CLs) are novel nonviral vectors widely used for delivering drugs or genes. However, applications of CLs are largely hampered by their cytotoxicity, partly because the potential mechanism underlying the ...