Now showing items 141-150 of 152
Incorporation of alkylthiol chains at C-5 of deoxyuridine
(Elsevier, 1993-08-27)
A series of alkylthiol-tether homologs at C-5 of 2'-deoxyuridine have been synthesized and incorporated into DNA oligomers through solid-phase DNA phosphoramidite synthesis. DNA-ligand disulfide crosslinks have been initially ...
Site-specific delivery of ethanehydroxy diphosphonate from refillable polyurethane reservoirs to inhibit bioprosthetic tissue calcification
(Elsevier, 1993-06)
Calcification (CALC) is the most frequent cause for the failure of bioprosthetic heart valves fabricated from glutaraldehyde-pretreated porcine aortic valve, and contributes to the failure of glutaraldehyde pretreated ...
Regulatory mechanisms underlying T cell integrin receptor function
(Elsevier, 1993-08)
Adhesion molecules allow lymphocytes to interact with and respond to the extracellular environment. Since these interactions must be essentially transient in nature, the function of lymphocyte adhesion molecules must be ...
Effect of mecillinam on peptidoglycan synthesis during the division cycle of Salmonella typhimurium 2616
(Elsevier, 1993)
The effects of mecillinam, ampicillin and cephalexin on peptidoglycan synthesis in Salmonella typhimurium 2616 have been studied at equivalent concentrations or "isoactivities". Using antibiotics at isoactivities allows a ...
Smooth Muscle Myosin Heavy Chain Locus (MYH11) Maps to 16p13.13-p13.12 and Establishes a New Region of Conserved Synteny between Human 16p and Mouse 16
(Elsevier, 1993-10)
The human smooth myosin heavy chain locus (MYH11) was mapped by fluorescence in situ hybridization to the middle of the p arm of chromosome 16 using a genomic cosmid clone containing coding sequences of the gene as probe. ...
Defect interactions on solid surfaces
(Elsevier, 1993-03-10)
A unified approach to the calculation of the elastic interaction between defects on a surface that describe, for example, steps, islands, and stress domains is presented. This is accomplished by determining the spatial ...
Alkylation of human albumin by the antimalarial artemisinin
(Elsevier, 1993-07-20)
The interaction between artemisinin and human serum was studied in vitro using [3H]-dihydroartemisinin and [14C]artemisinin. Approximately 20% of added drug was covalently bound to albumin in 24 hr. The results of electrospray ...
Clozapine's functional mesolimbic selectivity is not duplicated by the addition of anticholinergic action to haloperidol: a brain stimulation study in the rat
(Springer-Verlag, 1993-01)
This study examined whether the anticholinergic potency of the clinically superior antipsychotic drug clozapine contributes to clozapine's anatomically-selective functional inhibition of the mesolimbic dopamine (DA) system, ...
The efficacy of controlled release -sotalol-polyurethane epicardial implants for ventricular arrhythmias due to acute ischemia in dogs
(Elsevier, 1993-01)
Epicardially implanted -sotalol polyurethane composite matrices for preventing ischemic ventricular arrhythmias were studied in open chest dogs under general anesthesia. -sotalol was combined with a polyureapolyurethane ...
Immunocytochemistry of sequence-related neuropeptides in Drosophila
(Elsevier, 1993-06)
Based on structure, activity, and expression, the Drosophila drosulfakinin I peptide (DSK I; FDDY(OSO3H)GHMRFamide) is similar to the vertebrate peptide, cholecystokinin.1 Dromyosuppressin (DMS; TDVDHVFLRFamide) is an ...