Now showing items 5031-5040 of 5051
Rieske Non-heme Iron Oxygenases in Natural Product Biosynthesis
(2022)
Nature has evolved a striking array of enzymes that perform precise C-H bond functionalization reactions. Rieske oxygenases represent one of the most prevalent and underexploited enzyme classes that falls in this category. ...
Use of Secondary Sphere Hydrogen Bonds for Stabilization and Divergent Reactivity in Transition Metal Complexes
(2022)
This dissertation describes advances made in the synthesis and reactivity of first row transition metal complexes featuring ligands with secondary sphere hydrogen bonding moieties. Inspiration for these complexes comes ...
The Reactivity of Ni Complexes in Conjugated Polymer Synthesis
(2022)
Catalyst-transfer polymerization (CTP) is a living, chain-growth polymerization method used to synthesize conjugated polymers with control over molar mass, sequence, and end-group identity. CTP is one of the few chain-growth ...
Heterogenization of Molecular Electrocatalysts for Small Molecule Transformations
(2022)
The use of molecular electrochemical catalysts for small molecule transformations is a quickly growing and challenging field with numerous environmental, industrial, and agricultural applications. Molecular catalysts, while ...
Droplet Microfluidics Coupled to Capillary Electrophoresis and Mass Spectrometry for Pharmacological Applications
(2022)
Modern drug discovery relies on high-throughput screening for lead generation and protein target evaluation. There is a critical need to develop assays that not only have large-scale screening capabilities but provide ...
Low Temperature Electrodeposition of Epitaxial Silicon Thin Films
(2022)
This thesis explores the applicability of Si electrodeposition to the synthesis of crystalline Si at low temperatures. Electrodeposition has been long perceived as an ideal route for the synthesis of semiconductor materials ...
Earth Abundant Transition Metal Molecular Complexes for Water Splitting
(2024)
Further development and understanding of the chemistry of earth-abundant transition-metal molecular catalysts for water splitting will aid development of a sustainable hydrogen economy. If dihydrogen can be produced ...
Borane-Appended Ligand Design Strategies for Small Molecule Capture and Reactivity
(2024)
In nature, metalloenzymes act as the premier catalysts for small molecule activation and transformation. The high activity and selectivity of enzymatic processes are, in part, owed to the complex system of acidic residues ...
Designing Chemical- and Light-Activated Protein Switches for Regulating Peptide Functions
(2023)
Peptides serve important biological functions including neuromodulation, hormonal regulation, cell signaling, protein localization, and enzyme inhibition. The ability to modulate peptide functions with precision is invaluable ...
Electrochemical Oxidation of Bio-derivable Alcohols Using Inorganic Materials and Mediators
(2024)
Upcoming depletion of non-renewable fossil fuels provides an urgent prompt for reshaping the current structure of both direct energy sources and processing for industrial chemicals. Biorefinery hints an alternative pathway ...