Now showing items 71-80 of 336
Steroid Metabolism by Rabbit Olfactory-Specific P450 2G1
(Elsevier, 1994-12)
Cytochrome P450 2G1 (2G1), which is uniquely expressed in the olfactory mucosa in mammals, may have important physiological functions. In the present study, we have examined the catalytic activity of rabbit 2G1 toward a ...
DNA-binding and non-DNA-binding forms of the transformed glucocorticoid receptor
(Elsevier, 1992-03)
In this work we have probed the mechanism responsible for two non-DNA-binding states of the mouse glucocorticoid receptor. In the first case, transformed receptors were treated with hydrogen peroxide. It is known that ...
Assay of human plasma cortisone by liquid chromatography: normal plasma concentrations (between 8 and 10 a.m.) of cortisone and corticosterone
(Elsevier, 1993-04-02)
A high-performance liquid chromatographic method using ultraviolet detection to quantitate human plasma concentrations of cortisone simultaneously with cortisol and corticosterone is described. The method is based on the ...
Subset-specific co-stimulatory signals are required for IL-2 production but not growth inhibition responses by T cell hybrids specific for myelin basic protein
(Elsevier, 1992-03)
Two distinct types of T cell hybridomas (designated THYB-1 and THYB-2) were derived by fusing BW5147 thymoma cells with encephalitogenic T helper cells from Lewis rats. Both subsets required MHC-restricted presentation of ...
Topical delivery of liposomally encapsulated gamma-interferon
(Elsevier, 1992-06-15)
The extent of uptake of gamma interferon ([gamma]-IFN) in various strata of hairless mouse, human and hamster skin upon application of a liposomal formulation and an aqueous solution were determined by in vitro diffusion ...
A Continuous Spectrophotometric and Fluorometric Assay for Protein Tyrosine Phosphatase Using Phosphotyrosine-Containing Peptides
(Elsevier, 1993-05-15)
Two continuous assays for protein tyrosine phosphatases (PTPases) have been developed using phosphotyrosine containing peptide substrates. These assays are based on the marked differences in the spectra of the peptide ...
CD28 and staphylococcal enterotoxins synergize to induce MHC-independent T-cell proliferation
(Elsevier, 1992-11)
The bacterial exotoxins staphylococcal enterotoxin A and B (SEA and SEB) mediate disease through their effects on T lymphocytes. In this manuscript we have demonstrated that both SEA and SEB can directly activate purified ...
Elemental balancing of biomass and medium composition enhances growth capacity in high-density Chlorella vulgaris cultures
(Wiley Subscription Services, Inc., A Wiley Company, 1998-09-05)
The basic requirements for high-density photoautotrophic microalgal cultures in enclosed photobioreactors are a powerful light source and proper distribution of light, efficient gas exchange, and suitable medium composition. ...
Synthesis of high-affinity, hydrophobic monosaccharide derivatives and study of their interaction with concanavalin A, the pea, the lentil, and fava bean lectins
(Elsevier, 1992-12)
Concanavalin A (Con A) and agglutinins from the pea (PSA), lentil (LCH), and fava bean (VFA) constitute a group of -mannose/-glucose binding legume lectins. In addition to their sugar binding specificity, these lectins ...
IGF receptor function and regulation in autocrine human neuroblastoma cell growth
(Elsevier, 1993-10-20)
Insulin-like growth factor-II (IGF-II) and its receptors (type I and II IGF receptors) are expressed in the nervous system in a tissue and developmentally specific manner. We have previously shown that SH-SY5Y human ...