Now showing items 21-30 of 267
Gene expression of the insulin-like growth factors and their receptors in cultured human retinal pigment epithelial cells
(Elsevier, 1992-01)
Insulin-like growth factors I and II (IGF I and II) are polypeptides with both growth-promoting and insulin-like metabolic effects16,27. Immunoreactive IGF I is present in the retina14 and both IGF I and II are present in ...
Primary rat hepatocyte culture on 3D nanofibrous polymer scaffolds for toxicology and pharmaceutical research
(Wiley Subscription Services, Inc., A Wiley Company, 2011-01)
Primary rat hepatocytes are a widely used experimental model to estimate drug metabolism and toxicity. In currently used two-dimensional (2D) cell culture systems, typical problems like morphological changes and the loss ...
Short-Term Adrenalectomy Increases Glucocorticoid and Mineralocorticoid Receptor mRNA in Selective Areas of the Developing Hippocampus
(Elsevier, 1993-10)
In the central nervous system, adrenal steroids bind to two different types of corticosteroid receptors: glucocorticoid (GR) or mineralocorticoid (MR). In vitro biochemical and autoradiographic techniques have been used ...
Systemic hormonal and physiological abnormalities in anxiety disorders
(Elsevier, 1988)
Among the studies of systemic hormonal and physiological abnormalities associated with anxiety disorders, the most consistent and extensive findings suggest (a) peripheral adrenergic hyperactivity (including increases in ...
Reproduction numbers and thresholds in stochastic epidemic models I. Homogeneous populations
(Elsevier, 1991-12)
We compare threshold results for the deterministic and stochastic versions of the homogeneous SI model with recruitment, death due to the disease, a background death rate, and transmission rate [beta]cXY / N. If an infective ...
Microprinted feeder cells guide embryonic stem cell fate
(Wiley Subscription Services, Inc., A Wiley Company, 2011-10)
We introduce a non‐contact approach to microprint multiple types of feeder cells in a microarray format using immiscible aqueous solutions of two biopolymers. Droplets of cell suspension in the denser aqueous phase are ...
An idealized concept of the true cladistic character
(Elsevier, 1975-04)
Estimating evolutionary relationships is basic to the objectives of systematics. Comparative data, structured as taxonomic characters, are usually the essential considerations on which such estimates are founded. Some ...
Physiological changes during the adaptation of hybridoma cells to low serum and serum-free media
(Wiley Subscription Services, Inc., A Wiley Company, 1991-01-05)
Two murine hybridoma cell lines (167.4G5.3 and S3H5/Γ2bA2) were adapted to grow in low-serum and serum-free media by a weaning procedure. The changes in cell growth, metabolic, and antibody production rates with adaptation ...
Increased activity of ornithine decarboxylase in goldfish following optic nerve crush
(Elsevier, 1981-06)
Ornithine decarboxylase (ODC) activity increased in goldfish retina, brain, and kidney several days following unilateral intraorbital optic nerve crush. Activity in both retinas followed a similar time course, an elevation ...