Now showing items 321-330 of 337
(1) The Relationship of Protein Expression and Cell Division, (2) 3D Imaging of Cells Using Digital Holography, and (3) General Chemistry Enrollment at University of Michigan.
(2012)
Chapter 1: We evaluated the relationship between cell division and protein expression when using commercial poly(ethylenimine) (PEI)-based polyplexes. The membrane dye PKH26 was used to assess cell division, and cyan ...
Prioritization of Evolutionary Events for Immune Response Studies: Introgression, Selection, and Infectious Disease Among Indigenous Americans
(2020)
A history of exposure to infectious diseases has influenced the biology of Mesoamericans. From the urbanization of Mesoamerican communities to colonial contact in the 15th century, immune response to various pathogens have ...
Structure and Dynamics of Emotional Experience in Depression.
(2012)
Human emotional experience is extremely complex and dynamic. Multiple factors
contribute to the ever changing subjective experience of emotion. Exteroceptive
information from our senses, interoceptive information from ...
Cultivation of Enhanced Bioinformatic-Specific Pedagogical Manipulatives, Interventions, and Professional Development
(2022)
The education of bioinformatics, as an interdisciplinary science, can be negatively impacted by 1) incoming students attempting to negotiate complex concepts while lacking the educational scaffolding of the field’s constituent ...
Sex Differences in the Role of GPER1 in the Dorsolateral Striatum on Motivation and Reward
(2021)
There are sex differences in susceptibility to psychostimulant addiction, supported by clinical evidence and pre-clinical research models. In rodent models, female rats acquire a preference for cocaine at lower doses, ...
Making Sense of Multidimensional Health Data to Manage Chronic Conditions: Designing to Support Episode-Driven Data Interaction
(2022)
People with chronic health conditions, such as diabetes, are now able to capture large amounts of health data every day owing to improved medical and consumer sensing technology. These data, known as patient-generated data, ...
Persistent Pathogens and Incident Stroke in Mexican Americans.
(2012)
Stroke is the fourth leading cause of death and a leading cause of disability in adults in the US. Nearly 800,000 people suffer a stroke annually, and more than 143,000 deaths occur as a result. Hispanic Americans are the ...
Joint Mean and Covariance Modeling of Matrix-Variate Data
(2018)
This dissertation addresses theory, methodology, and applications for joint mean and covariance estimation with matrix-variate data. Chapters 2 and 3 consider joint mean and covariance estimation in the Kronecker product ...
Severe Illness Associated With Respiratory Viruses: Burden and Temporal Dynamics
(2020)
Acute lower respiratory tract infections (ALRI) are a substantial source of global morbidity and mortality, particularly among young children. Respiratory syncytial virus (RSV) and influenza are consistently observed to ...
Continuity and Change in Theory-of-Mind Development: A Neuroscientific Approach.
(2013)
This dissertation seeks a more comprehensive picture of the process of theory-of-mind development (an understanding that action is guided by internal mental states such as beliefs, desires, and intentions) by examining ...