Now showing items 61-70 of 640
Delayed neurotrophin treatment following deafness rescues spiral ganglion cells from death and promotes regrowth of auditory nerve peripheral processes: Effects of brain-derived neurotrophic factor and fibroblast growth factor
(Wiley Subscription Services, Inc., A Wiley Company, 2007-07)
The extent to which neurotrophic factors are able to not only rescue the auditory nerve from deafferentation-induced degeneration but also promote process regrowth is of basic and clinical interest, as regrowth may enhance ...
Evaluation of encapsulating and microporous nondegradable hydrogel scaffold designs on islet engraftment in rodent models of diabetes
(Wiley Periodicals, Inc., 2018-09)
Islet transplantation is a promising therapeutic option for type 1 diabetes mellitus, yet the current delivery into the hepatic portal vasculature is limited by poor engraftment. Biomaterials have been used as a means to ...
A microfluidic bioreactor with integrated transepithelial electrical resistance (TEER) measurement electrodes for evaluation of renal epithelial cells
(Wiley Subscription Services, Inc., A Wiley Company, 2010-11-01)
We have developed a bilayer microfluidic system with integrated transepithelial electrical resistance (TEER) measurement electrodes to evaluate kidney epithelial cells under physiologically relevant fluid flow conditions. ...
Pore-scale investigation of biomass plug development and propagation in porous media
(John Wiley & Sons, Inc., 2002-03-05)
Biomass plugging of porous media finds application in enhanced oil recovery and bioremediation. An understanding of biomass plugging of porous media was sought by using a porous glass micromodel through which biomass and ...
Developing multicomponent interventions using fractional factorial designs
(John Wiley & Sons, Ltd., 2009-09-20)
Multicomponent interventions composed of behavioral, delivery, or implementation factors in addition to medications are becoming increasingly common in health sciences. A natural experimental approach to developing and ...
Growth of Leuconostoc mesenteroides NRRL-B523 in an alkaline medium: Suboptimal pH growth inhibition of a lactic acid bacterium
(Wiley Subscription Services, Inc., A Wiley Company, 2005-01-05)
Bacterial profile modification (BPM), a form of tertiary oil recovery, diverts water from the water-flooded high-permeability zone into the oil-bearing low-permeability zone. During field use, exopolymer-producing bacteria ...
The nature of middle school learners' science content understandings with the use of on-line resources
(Wiley Subscription Services, Inc., A Wiley Company, 2003-03)
Early research on using the World Wide Web indicated that middle school students did not explore much and used Web tools naively. In response to these challenges, an on-line research engine, Artemis, was designed to provide ...
Generalizing the TITE-CRM to adapt for early- and late-onset toxicities
(John Wiley & Sons, Ltd., 2005)
Due to the staggered entry of subjects in phase I trials, some subjects will only be partially through the study when others are ready to be enrolled. Nonetheless, many phase I designs focus solely upon whether or not ...
Heat shock factor 1-deficient mice exhibit decreased recovery of hearing following noise overstimulation
(Wiley Subscription Services, Inc., A Wiley Company, 2005-08-15)
Heat shock proteins (Hsps) can enhance cell survival in response to stress. Heat shock factor 1 (Hsf1) is the major transcription factor that regulates stress-inducible Hsp expression. We previously demonstrated the ...
Semiparametric Bayesian modeling of random genetic effects in family-based association studies
(John Wiley & Sons, Ltd., 2009-01-15)
We consider the inference problem of estimating covariate and genetic effects in a family-based case-control study where families are ascertained on the basis of the number of cases within the family. However, our interest ...