Now showing items 1-10 of 4662
Role of B-Catenin Signaling in Adrenocortical Development and Tumorigenesis
Wnt/β-catenin signaling plays many important roles during mammalian development. In the adrenal cortex, perturbations in the signaling pathway are associated with abnormal development and adrenocortical tumorigenesis. Loss- ...
Generation of theta rhythm in medial entorhinal cortex of freely moving rats
A regular slow wave theta rhythm can be recorded in the medial entorhinal cortex (MEC) of freely moving rats during voluntary behaviors and paradoxical sleep. Electrode penetrations normal to the cortical layers proceeding ...
Amino acid substitution and chemical characterization of a Japanese variant of carbonic anhydrase I: CA I Hiroshima-1 (86 Asp → Gly)
(Kluwer Academic Publishers-Plenum Publishers; Plenum Publishing Corporation ; Springer Science+Business Media, 1981-06)
An electrophoretic variant of red cell carbonic anhydrase I, designated CA I Hiroshima-1, has been observed in 12 apparently unrelated individuals during a survey of 13,019 individuals from the cities of Hiroshima and ...
A Geometric Framework for Evaluating Rare Variant Tests of Association
(Wiley Periodicals, Inc., 2013-05)
The wave of next‐generation sequencing data has arrived. However, many questions still remain about how to best analyze sequence data, particularly the contribution of rare genetic variants to human disease. Numerous ...
Inhibition of Vesicular Glutamate Uptake by Rose Bengal-Related Compounds: Structure–Activity Relationship
(Kluwer Academic Publishers-Plenum Publishers; Springer Science+Business Media, Inc., 2005-03)
Synaptic vesicular accumulation of glutamate is a vital initial step in glutamate transmission. We have previously shown that Rose Bengal, a polyhalogenated fluorescein analog, is a potent inhibitor of glutamate uptake ...
Unrelated donor bone marrow transplantation using a chemotherapy-only preparative regimen for adults with high-risk acute myelogenous leukemia
(Wiley Subscription Services, Inc., A Wiley Company, 2007-01)
Limited data are available for adults undergoing unrelated donor (URD) BMT for AML using chemotherapy-only preparative regimens. Previous studies incorporated irradiation, included adults and children, and excluded secondary ...
Role of gangliosides in gonadotropin and cholera enterotoxin stimulated steroidogenesis in isolated rat ovarian cells
Ovarian cells isolated from 26 day old rats responded to hCG (10 ng/ml) and cholera enterotoxin (100 ng/ml) with a forty-five to fifty-fold increase in progesterone production. Both cholera enterotoxin and hCG-stimulated ...
Beitrag zum Problem der heterosynaptischen Facilitation in Aplysia californica
1. Heterosynaptic facilitation (H.S.F.) of single neurons in the central nervous system of Aplysia can be repeated virtually indefinitely, provided sufficient time is allowed for recovery between the trials.
A comparison of the responses of two tropical specialist herbivores to host plant patch size
The effects of host plant patch size on the abundances of two specialist herbivores (the chrysomelid beetle, Acalymma innubum and the pentatomid bug, Piezosternum subulatum ) were investigated in a natural forest community ...
Survival following salvage therapy for primary refractory peripheral T‐cell lymphomas (PTCL)
(Wiley Periodicals, Inc.American Society of Hematology, 2018-03)
Optimal salvage therapy for primary refractory peripheral T‐cell lymphomas (PTCL) and the role of hematopoietic stem cell transplant (SCT) remain poorly defined. We conducted a retrospective review of clinical outcomes and ...