Now showing items 1-10 of 23
Isolation and sequence analysis of CDC43, a gene involved in the controol of cell polarity in Saccharomyces cerevisiae
(Elsevier, 1990-05-31)
The Saccharomyces cerevisiae CDC43 gene product is involved in establishing cell polarity during the cell-division cycle. When grown at restrictive temperatures, temperature-sensitive cdc43 mutants are unable to form buds ...
Human chromosome 17 NotI linking clones and their use in long-range restriction mapping of the Miller-Dieker chromosome region (MDCR) in 17p13.3
(Elsevier, 1990-06)
A NotI linking library constructed from flow-sorted human chromosome 17 material was screened to aid in construction of a long-range restriction map of the Miller-Dieker chromosome region (MDCR) in 17p13.3. A total of 66 ...
A novel phosphate-regulated expression vector in Escherichia coli
(Elsevier, 1990-05-31)
The ugp promoter (pugp) responsible for expression of the binding-protein-dependent sn-glycerol-3-phosphate transport system in Escherichia coli was cloned into a small multicopy plasmid pTER5, a derivative of pBR322, ...
Linkage of the multiple endocrine neoplasia type 2B gene (MEN2B) to chromosome 10 markers linked to MEN2A
(Elsevier, 1990-10)
The syndrome of multiple endocrine neoplasia type 2B (MEN 2B) resembles that of MEN 2A in that both include medullary carcinoma of the thyroid, pheochromocytoma, and autosomal dominant inheritance, but is distinct in that ...
Mapping the human amylase gene cluster on the proximal short arm of chromosome 1 using a highly informative (CA)n repeat
(Elsevier, 1990-05)
The human amylase gene cluster includes a (CA)n repeat sequence immediately upstream of the [gamma]-actin pseudogene associated with the AMY2B gene. Analysis of this (CA)n repeat by PCR amplification of genomic DNA from ...
Localization of a human T-cell-specific gene, RANTES (D17S136E), to chromosome 17q11.2-q12
(Elsevier, 1990-03)
We report here the localization of the gene for a human T-cell-specific molecule, designated RANTES, to human chromosome region 17q11.2-q12 by in situ hybridization and analysis of somatic cell hybrids using a cDNA probe ...
Structure and chromosomal localization of the human thrombospondin gene
(Elsevier, 1990-04)
Thrombospondin (THBS1) is a large modular glycoprotein component of the extracellular matrix and contains a variety of distinct domains, including three repeating subunits (types I, II, and III) that share homology to an ...
Prenatal diagnosis and linkage disequilibrium with cystic fibrosis for markers surrounding D7S8
(Springer-Verlag, 1990-08)
Three polymorphic DNA markers surrounding the D7S8 locus were tested for their usefulness in the diagnosis of cystic fibrosis (CF) by linkage analysis. The markers correspond to the loci D7S424 and D7S426. These polymorphisms ...
Post-meiotic gene expression
(Elsevier, 1990)
Evolutionary arguments and well-designed experiments (based on false premises, however) bad suggested that post-meiotic gene expression did not occur in animals. The technique of molecular genetics have now clearly ...
Two subfamilies of murine retrotransposon ETn sequences
(Elsevier, 1990-02-14)
Early transposon (ETn) elements are 5.7-kb retrotransposons found in the murine genome. We have sequenced large portions of two ETn elements that have apparently transposed within the DNA of a murine myeloma cell line, ...