Now showing items 1-10 of 11
Syndrome X: Is it for real?
(Wiley Subscription Services, Inc., A Wiley Company, 1998)
The term syndrome X has been applied to the association of hypertension, non-insulin-dependent diabetes mellitus (NIDDM), android obesity, insulin resistance, and dyslipidemia. In this paper, based on population samples ...
Further localization of a gene for paroxysmal dystonic choreoathetosis to a 5-cM region on chromosome 2q34
(Springer-Verlag; Springer-Verlag Berlin Heidelberg, 1998-01)
Paroxysmal dystonic choreoathetosis (PDC) is a rare neurological disorder characterized by episodes of involuntary movement, involving the extremities and face, which may occur spontaneously or be precipitated by caffeine, ...
Reappraisal of studies concerning the genetic effects of the radiation of humans, mice, and Drosophila
(John Wiley & Sons, Inc., 1998)
No abstract.
TECHNICAL REPORT: Rapid confirmation of gene targeting in embryonic stem cells using two long-range PCR techniques
(Kluwer Academic Publishers; Chapman and Hall ; Springer Science+Business Media, 1998-03)
Gene targeting in mouse embryonic stem (ES) cells generally includes the analysis of numerous colonies to identify a few with mutations resulting from homologous recombination with a targeting vector. Thus, simple and ...
Dual role for the zeste-white3/shaggy -encoded kinase in mesoderm and heart development of Drosophila
(John Wiley & Sons, Inc., 1998)
A Drosophila homolog of the serine/threonine kinase GSK-3β, encoded by the zest-white3/shaggy gene ( zw3 ), has been implicated as a maternally provided antagonist of zygotic signaling by the secreted segmentation gene ...
Genetic structure of five susceptibility gene regions for coronary artery disease: disequilibria within and among regions
(Springer-Verlag; Springer-Verlag Berlin Heidelberg, 1998-09)
We analyzed two-locus disequilibria for 16 polymorphic loci of seven susceptibility genes for coronary artery disease located in five chromosomal regions distributed across four chromosomes. Included were the genes coding ...
Heart development in Drosophila and vertebrates: Conservation of molecular mechanisms
(John Wiley & Sons, Inc., 1998)
Vertebrate and insect ( Drosophila ) hearts look and function quite differently from each other. Nevertheless, during embryogenesis their mesodermal origin and initial assembly into a linear heart tube are comparable in ...
An ecological study of association between coronary heart disease mortality rates in men and the relative frequencies of common allelic variations in the gene coding for apolipoprotein E
(Springer-Verlag; Springer-Verlag Berlin Heidelberg, 1998-09)
Three common alleles, ɛ 2 , ɛ 3 , and ɛ 4 , of the gene coding for apolipoprotein E (apoE) have been identified as predictors of interindividual variation in measures of lipid and lipoprotein metabolism, and ultimately ...
Quantitative DNA pooling to increase the efficiency of linkage analysis in autosomal dominant disease
(Springer-Verlag; Springer-Verlag Berlin Heidelberg, 1998-02)
DNA pooling is an efficient method to rapidly perform genome-wide linkage scans in autosomal recessive diseases in inbred populations where affected individuals are likely to be homozygous for alleles near the disease gene ...
Physical mapping of the nail patella syndrome interval at 9q34: ordering of STSs and ESTs
(Springer-Verlag; Springer-Verlag Berlin Heidelberg, 1998-11)