Now showing items 1-10 of 38
Solute concentration in the kidney-- I. a model of the renal medulla and its limit cases
(Elsevier, 1976)
We develop a general model of the renal medulla that is similar in geometry to the models reported by others. Two solutes are assumed to be present, one to play the role of salt and the other that of urea and similarly ...
A game to help students comprehend enzyme structure and mechanism of action
(Elsevier, 1976-01)
Aspirin as a quantitative acetylating reagent for the fatty acid oxygenase that forms prostaglandins
(Elsevier, 1976-01)
A selective acetylation of the prostaglandin-forming fatty acid oxygenase (part of the prostaglandin "synthetase" system) occurs with 100 [mu]M concentrations of aspirin (acetylsalicylic acid). The amount of acetylation, ...
Synthesis of potential antiprogestogens
(Elsevier, 1976-01)
Acylated derivatives of 17[alpha]-hydroxyprogesterone were prepared in order to test the hypothesis that dialkylamino alkyl moieties have the effect of transforming progestogens into antiprogestogens. This approach has ...
A shift from phospholipid to triglyceride synthesis when cell division is inhibited by trans-fatty acids
(Elsevier, 1976-10)
The yeast mutant Saccharomyces cerevisiae (KD 46) requires added unsaturated fatty acid for growth. When cell growth was inhibited by the presence of trans-acids there was a marked inhibition of oleate esterification into ...
The effects of changes in thyroid function on testis 32P uptake and the response to gonadotropin in the chick
(Elsevier, 1976-04)
Propylthiouracil (PTU)-induced hypothroidism has been shown to produce a significant increase in the uptake of radiophosphorus (32P) by the testes of young chicks. Continued investigation of this effect demonstrated that ...
Some properties of RAT liver mitochondrial RNA polymerase
(Kluwer Academic Publishers; Dr. W. Junk b.v. Publishers ; Springer Science+Business Media, 1976-12)
A rapid method suitable for purifying large amounts of mitochondria from rat liver using isopycnic zonal centrifugation is described. The RNA polymerase isolated from the purified mitochrondria was found associated with ...
Cooperative effects of bacterial mutations affecting [lambda] N gene expression : II. Isolation and characterization of mutations in the rif region
(Elsevier, 1976-08)
We report the isolation and initial characterization of a class of mutations, Snu, that map near the rif locus on the Escherichia coli chromosome. Snu mutations inhibit the growth of phage [lambda], an effect primarily ...
Studies on the cellular site of action of macrophage RNA-antigen complexes
(Elsevier, 1976-01)
Nonadherent spleen cell populations exposed in vitro to ribonucleic acid-rich preparations from mouse macrophages that had been incubated with human [gamma]-globulin (RNA : HGG) were able to produce specific antibody, as ...
Studies on hydroperoxide-dependent substrate hydroxylation by purified liver microsomal cytochrome P-450
(Elsevier, 1976-08)
Highly purified liver microsomal cytochrome P-450 catalyzes the hydroperoxide-dependent hydroxylation of a variety of substrates in the absence of NADPH, NADPH-cytochrome P-450 reductase, and molecular oxygen. The addition ...