Now showing items 1-10 of 843
A Geometric Framework for Evaluating Rare Variant Tests of Association
(Wiley Periodicals, Inc., 2013-05)
The wave of next‐generation sequencing data has arrived. However, many questions still remain about how to best analyze sequence data, particularly the contribution of rare genetic variants to human disease. Numerous ...
Survival following salvage therapy for primary refractory peripheral T‐cell lymphomas (PTCL)
(Wiley Periodicals, Inc.American Society of Hematology, 2018-03)
Optimal salvage therapy for primary refractory peripheral T‐cell lymphomas (PTCL) and the role of hematopoietic stem cell transplant (SCT) remain poorly defined. We conducted a retrospective review of clinical outcomes and ...
Compartmentalized Photoreactions within Compositionally Anisotropic Janus Microstructures
(WILEY-VCH Verlag, 2011-03-02)
We demonstrate spatially controlled photoreactions within bicompartmental microparticles and microfibers. Selective photoreactions are achieved by anisotropic incorporation of photocrosslinkable poly(vinyl cinnamate) in ...
A prediction model for colon cancer surveillance data
(Wiley Periodicals, Inc.CRC Press, Inc., 2015-08-15)
Lumbar Vertebral Body Bone Microstructural Scaling in Small to Medium‐Sized Strepsirhines
(Wiley Subscription Services, Inc., A Wiley Company, 2013-02)
Bone mass, architecture, and tissue mineral density contribute to bone strength. As body mass (BM) increases any one or combination of these properties could change to maintain structural integrity. To better understand ...
Substrate interaction defects in histidylâ tRNA synthetase linked to dominant axonal peripheral neuropathy
(University of WashingtonWiley Periodicals, Inc., 2018-03)
Histidylâ tRNA synthetase (HARS) ligates histidine to cognate tRNA molecules, which is required for protein translation. Mutations in HARS cause the dominant axonal peripheral neuropathy Charcotâ Marieâ Tooth disease ...
Ontogenetic relationships between cranium and mandible in coyotes and hyenas
(Wiley Subscription Services, Inc., A Wiley Company, 2011-06)
Developing animals must resolve the conflicting demands of survival and growth, ensuring that they can function as infants or juveniles while developing toward their adult form. In the case of the mammalian skull, the ...
Improving on analyses of self-reported data in a large-scale health survey by using information from an examination-based survey
(John Wiley & Sons, Ltd., 2010-02-28)
Common data sources for assessing the health of a population of interest include large-scale surveys based on interviews that often pose questions requiring a self-report, such as, ‘Has a doctor or other health professional ...
Computational analysis of unassigned high-quality MS/MS spectra in proteomic data sets
(WILEY-VCH Verlag, 2010-07)
In a typical shotgun proteomics experiment, a significant number of high-quality MS/MS spectra remain “unassigned.” The main focus of this work is to improve our understanding of various sources of unassigned high-quality ...