Now showing items 1-10 of 103
Effect of Neuropeptide Y on Natural Killer Activity of Normal Human Lymphocytes
(Elsevier, 1993-03)
The in vitro effect of neuropeptide Y (NPY) on natural killer (NK) cell activities of normal lymphocytes was investigated. NPY at 10-9 to 10-12M concentrations produced significant suppression of NK activity against K 562 ...
Interactive effects of subanesthetic ketamine and subhypnotic lorazepam in humans
(Springer-Verlag; Springer-Verlag Berlin Heidelberg, 1998-01)
Ketamine is an N -methyl- D -aspartate (NMDA) receptor antagonist with psychotogenic and dissociative effects in healthy humans. These cognitive and perceptual effects in humans are reportedly reduced by benzodiazepine ...
CCK antagonists reveal that CCK-8 and JMV-180 interact with different sites on the rat pancreatic acinar cell CCKA receptor
(Elsevier, 1994)
The ability of CCKA antagonists to inhibit full and partial CCK agonists of the rat pancreatic acinar cell CCKA receptor has been studied. When isolated rat pancreatic acini were superfused with CCK-8 (10 pM-1 nM) or CCK-4 ...
Selective inhibition by alcohol and cortisol of natural killer cell activity of lymphocytes from cord blood
(Elsevier, 1994-12)
1. 1. The immunosuppressive effects of drugs such as alcohol or hormones such as cortisol may be age-related. To test this hypothesis, the authors investigated the in vitro effects of ethanol (EtOH) and cortisol on Natural ...
Effects of tobacco smoking on the topographic EEG I
(Elsevier, 1994-09)
1. 1. The EEG and cardiovascular effects of smoking tobacco cigarettes of varying nicotine content were studied in Japanese chronic tobacco smokers.2. 2. Thirteen female and fifteen male adult normal volunteers were recruited ...
Dexamethasone attenuation of the cortisol response to nicotine in smokers
(Springer-Verlag, 1990-06)
The effect of corticosteroids upon the cortisol response to nicotine from smoking was investigated in five heavy smokers. Corticosteroid activity was manipulated by administering dexamethasone, a synthetic glucocortoicoid ...
The effects of menstrual phase and nicotine abstinence on nicotine intake and on biochemical and subjective measures in women smokers: a A preliminary report
(Elsevier, 1992-11)
Nicotine intake, menstrual and smoking withdrawal symptomatology, and baseline cortisol and MHPG were assessed in nine women smokers under conditions of ad lib smoking and overnight abstinence in three menstrual phases ...
Effects of neuropeptide Y, insulin, 2-deoxyglucose, and food deprivation on food-motivated behavior
(Springer-Verlag, 1995-08)
The current study demonstrates the ability of neuropeptide Y (NPY) to increase break points under a progressive ratio 1 (PR1) reinforcement schedule. An initial response resulted in delivery of a food reinforcer (45 mg ...
Glucocorticoid-reinforced responding in the rhesus monkey
(Springer-Verlag; Springer-Verlag Berlin Heidelberg, 1999-11)
Rationale: Glucocorticoids have been reported to have rewarding effects in rats and may lead to drug-seeking behavior in humans under some circumstances. Objectives: The present study investigated whether glucocorticoids ...
Gene expression of the insulin-like growth factors and their receptors in cultured human retinal pigment epithelial cells
(Elsevier, 1992-01)
Insulin-like growth factors I and II (IGF I and II) are polypeptides with both growth-promoting and insulin-like metabolic effects16,27. Immunoreactive IGF I is present in the retina14 and both IGF I and II are present in ...