Now showing items 1-10 of 645
High levels of non-activated receptors in glucocorticoid-sensitive S49wt mouse lymphoma cells incubated with dexamethasone
(Elsevier, 1994-10)
Upon agonist binding the heteromeric glucocorticoid receptor complex under goes a conformational change (receptor activation). This event involves the dissociation of a dimer of 90 kDa heat shock proteins. Whereas receptor ...
Relationship between the subunit structure of insulin receptor and its competence to bind insulin and undergo phosphorylation
(Elsevier, 1984-11-01)
Insulin receptor partially purified from human placenta by chromatography on immobilized wheat germ agglutinin was subjected to affinity cross linking to determine the relationship between the subunit structure of the ...
Leukotriene C4 induces vasogenic cerebral edema in rats
(Elsevier, 1984-06)
Leukotriene C4 (LTC4) is reported to neither contract nor relax isolated human cerebra artdial strips (1), but in skin LTC4 will increase vascular permeability in post capillary venules, increase blood flow (2) and elicit ...
Characterization of gastrin amidation in the rat and porcine antrum: comparison with the pituitary
(Elsevier, 1990-04-24)
The formation of biologically active gastrin from glycine-extended processing intermediates occurs via the action of a peptide [alpha]-amidating enzyme. The observation that gastrin exists primarily as unamidated precursors ...
Properties of yeast pyruvate decarboxylase and their modification by proteolytic enzymes : I. Stability of decarboxylases from wild-type and mutant strains
(Elsevier, 1968)
High concentrations of inorganic phosphate and ammonium sulfate stabilize yeast pyruvate decarboxylase to heating at 60 [deg] for long periods of time in the presence of TPP and Mg+. When heated at 60 [deg] in phosphate ...
MoFe Cofactor of nitrogenase: Extraction, purification, and characterization
(Elsevier, 1989-08)