Now showing items 1-10 of 23
Computational analysis of unassigned high-quality MS/MS spectra in proteomic data sets
(WILEY-VCH Verlag, 2010-07)
In a typical shotgun proteomics experiment, a significant number of high-quality MS/MS spectra remain “unassigned.” The main focus of this work is to improve our understanding of various sources of unassigned high-quality ...
Multifunctional Magnetoplasmonic Nanoparticle Assemblies for Cancer Therapy and Diagnostics (Theranostics)
(WILEY-VCH Verlag, 2010-01-18)
In this work, we describe the preparation and biomedical functionalities of complex nanoparticle assemblies with magnetoplasmonic properties suitable for simultaneous cancer therapy and diagnostics (theranostics). Most ...
A guided tour of the Trans-Proteomic Pipeline
(WILEY-VCH Verlag, 2010-03)
The Trans-Proteomic Pipeline (TPP) is a suite of software tools for the analysis of MS/MS data sets. The tools encompass most of the steps in a proteomic data analysis workflow in a single, integrated software system. ...
Quantitative Determination of High Charge Density Polyanion Contaminants in Biomedical Heparin Preparations Using Potentiometric Polyanion Sensors
(WILEY-VCH Verlag, 2010-01)
Quantification of oversulfated chondroitin sulfate (OSCS) in biomedical heparin preparations is achieved using a recently described potentiometric polyanion sensor-based approach operated in a kinetic mode of analysis. ...
Non-Glycosidically Linked Pseudodisaccharides: Thioethers, Sulfoxides, Sulfones, Ethers, Selenoethers, and Their Binding to Lectins
(WILEY-VCH Verlag, 2010-04)
Hydrolytically stable non-glycosidically linked tail-to-tail pseudodisaccharides are linked by a single bridging atom remote from the anomeric centre of the constituent monosaccharides. Some such pseudodisaccharides with ...
Multifunctional Micro- and Nanoparticles – Quo vadis ?
(WILEY-VCH Verlag, 2010-01-18)
No Abstract.
Influence of Solute Charge and Hydrophobicity on Partitioning and Diffusion in a Genetically Engineered Silk-Elastin-Like Protein Polymer Hydrogel
(WILEY-VCH Verlag, 2010-10-08)
The influence of solute hydrophobicity and charge on partitioning and diffusion in physically crosslinked networks of a genetically engineered SELP polymer was investigated. A series of fluorescent dyes were used to assess ...
Glycoproteomics in neurodegenerative diseases
(Wiley Subscription Services, Inc., A Wiley Company, 2010-01)
Protein glycosylation regulates protein function and cellular distribution. Additionally, aberrant protein glycosylations have been recognized to play major roles in human disorders, including neurodegenerative diseases. ...
Development of selected reaction monitoring-MS methodology to measure peptide biomarkers in prostate cancer
(WILEY-VCH Verlag, 2010-10)
Prostate cancer is a leading cause of cancer-related death. The current modality of diagnosis, the measurement of serum PSA, not only suffers from lack of specificity, but does not distinguish clinical cases in which current ...