Now showing items 1-10 of 16
Highlights of B/D‐HPP and HPP Resource Pillar Workshops at 12th Annual HUPO World Congress of Proteomics
(Wiley Periodicals, Inc., 2014-05)
Existence of a Glassy Layer in the Polymer‐ N anosheet Interface: Evidence from Molecular Dynamics
(Wiley Periodicals, Inc., 2014-01)
Protease‐Sensitive PEG Hydrogels Regulate Vascularization In Vitro and In Vivo
(Wiley Periodicals, Inc., 2014-10)
Forming functional blood vessel networks in engineered or ischemic tissues is a significant scientific and clinical hurdle. Poly(ethylene glycol) (PEG)‐based hydrogels are adapted to investigate the role of mechanical ...
Comparison of Antidepressant‐Like and Abuse‐Related Effects of Phencyclidine in Rats
(National Research CouncilWiley Periodicals, Inc., 2014-12)
Preclinical Research N ‐methyl‐D‐aspartate ( NMDA ) receptor antagonists, such as ketamine, have emerged as novel candidate treatments for major depressive disorder, but abuse potential of these agents is a concern. ...
The Histone Methyltransferase DOT1L: Discovery of Small-Molecule Inhibitors and its Role in Wnt Signaling.
(2014)
Covalent post translational modifications of histone proteins are an important mechanism of epigenetic gene regulation that modulate chromatin structure. Methylation of histone lysine residues is one of several chemical ...
Synthesis and On‐Demand Gelation of Multifunctional Poly(ethylene glycol)‐Based Polymers
(Wiley Periodicals, Inc., 2014-04)
Revisiting the identification of canonical splice isoforms through integration of functional genomics and proteomics evidence
(Wiley Periodicals, Inc., 2014-12)
Overcoming Cancer Multidrug Resistance by Codelivery of Doxorubicin and Verapamil with Hydrogel Nanoparticles
(Humana PressWiley Periodicals, Inc., 2014-08)
The efficacy of chemotherapy is often inhibited by multidrug resistance (MDR). A highly engineerable hydrogel nanoparticle (NP) serves as a carrier for the optimal codelivery to tumor cells of the chemodrug, doxorubicin ...
Label‐free profiling of skeletal muscle using high‐definition mass spectrometry
(Departments of Environmental Health and Biostatistics, University of Washington, Seattle, WAWiley Periodicals, Inc., 2014-10)
The Role of Topological Constraints in RNA Tertiary Folding and Dynamics.
(2014)
Functional RNA molecules must fold into highly complex three-dimensional (3D) structures and undergo precise structural dynamics in order to carry out their biological functions. However, the principles that govern RNA 3D ...