Now showing items 1-10 of 31
Inhibition of cellular ATP-hydrolyzing activity by tricyclic antidepressants and phenothiazine tranquilizers
(Elsevier, 1975-05-01)
In a variety of cellular and subcellular preparations, total ATP-hydrolyzing activity was potently inhibited by tricyclic antidepressants (TA) and phenothiazine tranquilizers (PT). In leukocytes, preincubation of the cells ...
Properties of the genome in normal and SV-40 transformed WI-38 human diploid fibroblasts. III. Turnover of nonhistone chromosomal proteins and their phosphate groups
(Elsevier, 1975-04-01)
The turnover of nonhistone chromosomal proteins and their phosphate groups was compared in normal and in SV-40 virus transformed WI-38 human diploid fibroblasts. Cells were pulse labelled with tryptophan-3H and 32P for 30 ...
Enzyme stereoselectivity: The reversible reaction catalyzed by 2-keto-4-hydroxyglutarate aldolase of Escherichia coli
(Elsevier, 1975-08-04)
SummaryThe condensation of [3-3H3]-pyruvate with glyoxylate in 3HOH to form [3-3H2]-ketohydroxyglutarate was catalyzed by ketohydroxyglutarate aldolase of Escherichia coli to study the stereochemical behavior of the enzyme. ...
Drug inhibitable ecto-ATPase in leukocytes
(Elsevier, 1975-05-01)
In rat leukocytes, the total ATP-hydrolyzing activity was highest when determined in cells with an intact plasma membrane. The ecto-ATPase, exhibiting a Km for ATP of 0.3 mM, was inhibited 30% by sulfhydryl reagents, whereas ...
Citrulline metabolism in normal and citrullinemic human lymphocyte lines
(Kluwer Academic Publishers-Plenum Publishers; Plenum Publishing Corporation ; Springer Science+Business Media, 1975-08)
Citrullinemia is one of the five aminoacidurias associated with the Krebs-Henseleit urea cycle. A long-term lymphocyte line (UM-21) derived from a patient with this disease and nine of ten clones of this line were found ...
An idealized concept of the true cladistic character
(Elsevier, 1975-04)
Estimating evolutionary relationships is basic to the objectives of systematics. Comparative data, structured as taxonomic characters, are usually the essential considerations on which such estimates are founded. Some ...
Effects of hypoxia on the distribution of calcium in arterial smooth muscle cells of rats and swine
(Springer-Verlag, 1975-03)
Exposure to hypoxia caused an increase in the hematocrit and right heart weight of experimental rats, but did not affect calcium-45 uptake by pulmonary arterial smooth muscle cells. However, autoradiographic studies showed ...
Kynurenine metabolism in rats: Some hormonal factors affecting enzyme activities
(Elsevier, 1975-07-15)
The effects of certain long-term hormonal treatments of male and female rats on the activities of several enzymes involved in kynurenine synthesis and degradation were determined to further rationalize previously observed ...
L-kynurenine aminotransferase and L-[alpha]-aminoadipate aminotransferase. I. Evidence for identity
(Elsevier, 1975-01-20)
SummaryThe following observations strongly suggest that L-kynurenine aminotransferase (KAT) and L-[alpha]-aminoadipate aminotransferase (AAT) activities are associated with the same protein: 1. a similar distribution in ...
Dual control of lysogeny by bacteriophage P22: An antirepressor locus and its controlling elements
(Elsevier, 1975-02-05)
Two distantly linked clusters of genes on the Salmonella typhimurium phage P22 chromosome are involved in the control of lysogeny and superinfection immunity. One cluster consists of genes c1, c2, and c3, which are primarily ...