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Systems analysis of dynamic transcription factor activity identifies targets for treatment in Olaparib resistant cancer cells
(Wiley Periodicals, Inc.Systems Biology, 2017-09)
The development of resistance to targeted therapeutics is a challenging issue for the treatment of cancer. Cancers that have mutations in BRCA, a DNA repair protein, have been treated with poly(ADP‐ribose) polymerase (PARP) ...