Now showing items 1-8 of 8
Immunotherapeutic and Diagnostic Potential of Engineered Materials
(2022)
Globally breast cancer has the highest rates of incidence and mortality among women, and the progression of localized breast cancer to metastatic disease is associated with a stark decrease in survival. Although robust ...
Organic Room-Temperature Phosphorescence Materials: from Fundamental Triplet Exciton Modulations to Novel Applications in Biosensing and Bioimaging
(2021)
Metal-free purely organic phosphors are an emerging class of room-temperature phosphorescence (RTP) materials and have attracted great attention over the past decade, owning to their potentials in a variety of advanced ...
Temporal and Spatial Nanobiomaterials for Tissue Engineering and Drug Delivery
(2020)
The intersection of materials science, biology, and nanotechnology has allowed for the development of advanced nanobiomaterials for tissue engineering and drug delivery. With more knowledge of how physical and chemical ...
Multidisciplinary Study of Soft Shape Morphing Systems
(2021)
Nature abounds with examples of shape morphing systems where an entity either gradually grows into a complex 3-D shape pattern or rapidly morphs into a new configuration. Inspired by the shape shifting capabilities of ...
Systematic Improvement of Quantification and Formulation of Synthetic Protein Nanoparticles for Gene Delivery
(2022)
Gene therapy is a promising field for the generation of new and more effective therapies, but its application is stymied by the lack of safe and efficient delivery vehicles. Furthermore, gene delivery system optimization ...
Polymer Nanoparticle Design for Ovarian Cancer Therapies
(2021)
Ovarian cancer is the fifth leading cause of cancer related death in females and current clinical treatments have low patient survival rates. Nanoparticle drug delivery has been promoted as an effective therapy, however ...
The Role of the Tumor Microenvironment in Cancer Stem Cell Regulation and the Development of Chemoresistance in Ovarian Cancer
(2021)
Tumors are a complex mixture of cancer cells, non-cancer cells, extracellular matrix, and other stimuli. To maximize clinical translation of in vitro models, it is critical to recapitulate the high degree of complexity ...
Engineering Multifunctional Nanoparticles: Applied Nanoscale Therapeutics
(2022)
Decades of research towards the development of nanomedicines have, to date, yielded minimal
clinical impact. Focused particularly on the treatment of cancer, the relatively low
number of pursued technologies to reach the ...