Now showing items 1-10 of 2816
Generation of theta rhythm in medial entorhinal cortex of freely moving rats
(Elsevier, 1980-05-05)
A regular slow wave theta rhythm can be recorded in the medial entorhinal cortex (MEC) of freely moving rats during voluntary behaviors and paradoxical sleep. Electrode penetrations normal to the cortical layers proceeding ...
Inhibition of Vesicular Glutamate Uptake by Rose Bengal-Related Compounds: Structure–Activity Relationship
(Kluwer Academic Publishers-Plenum Publishers; Springer Science+Business Media, Inc., 2005-03)
Synaptic vesicular accumulation of glutamate is a vital initial step in glutamate transmission. We have previously shown that Rose Bengal, a polyhalogenated fluorescein analog, is a potent inhibitor of glutamate uptake ...
Synthetic Strategies and Parameters Involved in the Synthesis of Oligodeoxyribonucleotides According to the Phosphoramidite Method
(Wiley Periodicals, Inc.Plenum, 2000-02)
The phosphoramidite approach has had a major impact on the synthesis of oligonucleotides. This unit describes parameters that affect the performance of this method for preparing oligodeoxyribonucleotides, as well as a ...
High levels of non-activated receptors in glucocorticoid-sensitive S49wt mouse lymphoma cells incubated with dexamethasone
(Elsevier, 1994-10)
Upon agonist binding the heteromeric glucocorticoid receptor complex under goes a conformational change (receptor activation). This event involves the dissociation of a dimer of 90 kDa heat shock proteins. Whereas receptor ...
Relationship between the subunit structure of insulin receptor and its competence to bind insulin and undergo phosphorylation
(Elsevier, 1984-11-01)
Insulin receptor partially purified from human placenta by chromatography on immobilized wheat germ agglutinin was subjected to affinity cross linking to determine the relationship between the subunit structure of the ...
Stress induced grooming in the rat -- An endorphin mediated syndrome
(Elsevier, 1979-07)
Exposure of adult male Sprague--Dawley rats to a non-traumatic noise-light stress procedure subsequently increased grooming behavior in a novel environment. The grooming syndrome was marginally facilitated by adrenalectomy ...
Leukotriene C4 induces vasogenic cerebral edema in rats
(Elsevier, 1984-06)
Leukotriene C4 (LTC4) is reported to neither contract nor relax isolated human cerebra artdial strips (1), but in skin LTC4 will increase vascular permeability in post capillary venules, increase blood flow (2) and elicit ...