Now showing items 1-7 of 7
Extraction of aminoglycoside antibiotics with reverse micelles
(John Wiley & Sons, Ltd., 1996-01)
The reverse micelle system of sodium di-2-ethylhexyl phosphate was used to extract aminoglycoside antibiotics, neomycin and gentamicin. The aminoglycosides can be efficiently extracted into a reverse micelle solution, and ...
Dependence of fluorodeoxyuridine-induced cytotoxicity and megabase DNA fragment formation on S phase progression in HT29 cells
(Springer-Verlag; Springer-Verlag Berlin Heidelberg, 1996-02)
The relationship between cell cycle progression and induction of DNA double-strand breaks and cytotoxicity by exposure to fluorodeoxyuridine (FdUrd) was studied in HT29 human colon cancer cells. Fractionation of drug-treated ...
Treatment of Gaucher disease with an enzyme inhibitor
(Kluwer Academic Publishers; Chapman & Hall ; Springer Science+Business Media, 1996-04)
The hypothesis is offered predicting that Caucher patients could be treated with a drug that slows the synthesis of glucosylceramide, the lipid that accumulates in this disorder. The present therapeutic approach involves ...
Structural requirements for binding to the δ opioid receptor: Alkyl replacements at the third residue of deltorphin I
(Kluwer Academic Publishers; ESCOM Science Publishers B.V. ; Springer Science+Business Media, 1996-01)
The naturally occurring heptapeptide deltorphin I (Tyr- d -Ala-Phe-Asp-Val-Val-Gly-NH 2 ) exhibits extremely high affinity and selectivity for the δ opioid receptor. In an ongoing investigation of the features of this ...
Characterization of gangliosides from Ehrlich ascites tumour cells and their variants
(Kluwer Academic Publishers; Chapman & Hall ; Springer Science+Business Media, 1996-04)
Differences in the nature of the gangliosides present in two types of Ehrlich ascites tumour (EAT) cells, the adherent and non-adherent EAT cells, were studied. Gangliosides were isolated by DEAE Sephadex column chromatography ...
Studies of the action of ceramide-like substances ( d - and l -PDMP) on sphingolipid glycosyltransferases and purified lactosylceramide synthase
(Kluwer Academic Publishers; Chapman & Hall ; Springer Science+Business Media, 1996-06)
We have studied the effects of D -threo-1-phenyl-2-decanoylamino-3-morpholino-1-propanol ( D -PDMP) and its L -enantiomer on glycosphingolipids in cultured normal human kidney proximal tubular cells. We found that D -PDMP ...
First-principles study of the α-Al 2 O 3 (0001)/Cu(111) interface
(Kluwer Academic Publishers; Springer Science+Business Media, 1996-12)
Adhesive energetics and interfacial electronic structures have been computed from first principles for the Cu/Al 2 O 3 interface. Recent transmission electron microscopy results of Cu grown by molecular beam epitaxy on Al ...