Now showing items 1-10 of 44
Injectable microparticle-gel system for prolonged and localized lidocaine release. I. In vitro characterization
(Wiley Subscription Services, Inc., A Wiley Company, 2004-09-01)
Current treatment protocol for postoperative pain is to infuse anesthetic solution around nerves or into the epidural space. This clinical practice is beset by the short duration of the anesthetic effect unless the infusion ...
Synthetic nano-fibrillar extracellular matrices with predesigned macroporous architectures
(John Wiley & Sons, Inc., 2000-11)
Scaffolding plays a pivotal role in tissue engineering. To mimic the architecture of a natural extracellular matrix component—collagen, nona-fibrous matrices have been created with synthetic biodegradable polymers in our ...
Engineering vascular networks in porous polymer matrices
(Wiley Subscription Services, Inc., A Wiley Company, 2002-06-15)
Enhanced vascularization is critical to the treatment of ischemic tissues and the engineering of new tissues and organs. We have investigated whether sustained and localized delivery of vascular endothelial growth factor ...
Engineering new bone tissue in vitro on highly porous poly(Α-hydroxyl acids)/hydroxyapatite composite scaffolds
(John Wiley & Sons, Inc., 2001-02)
Engineering new bone tissue with cells and a synthetic extracellular matrix (scaffolding) represents a new approach for the regeneration of mineralized tissues compared with the transplantation of bone (autografts or ...
Nano-fibrous scaffolding architecture selectively enhances protein adsorption contributing to cell attachment
(Wiley Subscription Services, Inc., A Wiley Company, 2003-11-01)
Tissue engineering aims at resolving problems such as donor shortage and immune rejection faced by transplantation. Scaffolds (artificial extracellular matrices) have critical roles in tissue engineering. Recently, we ...
Rotator Cuff Tendinosis in an Animal Model: Role of Extrinsic and Overuse Factors
(Kluwer Academic Publishers-Plenum Publishers; Biomedical Engineering Society ; Springer Science+Business Media, 2002-09)
The rat shoulder animal model has been used previously to study the role of intrinsic injury (modeled as an acute insult to the tendon), extrinsic injury (modeled as external subacromial impingement), and overuse factors ...
Polymeric Scaffolds for Bone Tissue Engineering
(Kluwer Academic Publishers-Plenum Publishers; Biomedical Engineering Society ; Springer Science+Business Media, 2004-03)
Bone tissue engineering is a rapidly developing area. Engineering bone typically uses an artificial extracellular matrix (scaffold), osteoblasts or cells that can become osteoblasts, and regulating factors that promote ...
Fabrication and in vitro testing of polymeric delivery system for condensed DNA
(Wiley Subscription Services, Inc., A Wiley Company, 2003-12-15)
Polyethylenimine (PEI) was combined with plasmid DNA and freeze dried following the addition of sucrose as a lyoprotectant and pore-forming agent. Freeze-dried PEI DNA condensates were dry mixed with granular polylactideglycolic ...
Poly(glutamic acid) poly(ethylene glycol) hydrogels prepared by photoinduced polymerization: Synthesis, characterization, and preliminary release studies of protein drugs
(Wiley Subscription Services, Inc., A Wiley Company, 2002-10)
A class of new biodegradable hydrogels based on poly(ethylene glycol) methacrylate-graft-poly(glutamic acid) and poly(ethylene glycol) dimethacrylate was synthesized by photoinduced polymerization. Because all the polymeric ...
Room-temperature preparation and characterization of poly (ethylene glycol)-coated silica nanoparticles for biomedical applications
(Wiley Subscription Services, Inc., A Wiley Company, 2003-09-15)
Monodisperse, spherical, polyethylene glycol (PEG)–coated silica nanoparticles have been prepared at room temperature and characterized for the purpose of biomedical applications. The particles were synthesized by the ...