Now showing items 1-10 of 53
Imaging Changes after Stereotactic Radiosurgery of Primary and Secondary Malignant Brain Tumors
(Kluwer Academic Publishers; Springer Science+Business Media, 2002-01)
After radiosurgery of malignant tumors, it can be difficult to discriminate between transient treatment effects, radiation necrosis, and tumor progression on post-treatment imaging. Misinterpretation of an enlarging lesion ...
Expedition Inspiration Fund for Breast Cancer Research Meeting 2003
(Kluwer Academic Publishers; Springer Science+Business Media, 2003-07)
Identifying and Validating Causal Genetic Alterations in Human Breast Cancer
(Kluwer Academic Publishers; Springer Science+Business Media, 2003-04)
An important mechanism for the activation of proto-oncogenes in human breast and other cancers is gene amplification, which results in gene overexpression at both the message and the protein levels. Recent studies have ...
Multiple Signaling Pathways are Activated During Insulin-like Growth Factor-I (IGF-I) Stimulated Breast Cancer Cell Migration
(Kluwer Academic Publishers; Springer, 2005-09)
In order to display the full metastatic phenotype, the cancer cell must acquire the ability to migrate. In breast cancer, we have previously shown that insulin-like growth factor I (IGF-I) enhances cell motility in the ...
Breast Cancer Research and Treatment
(Kluwer Academic Publishers; Springer Science+Business Media, 2001-09)
Intratumoral injection of BCNU in ethanol (DTI-015) results in enhanced delivery to tumor – a pharmacokinetic study
(Kluwer Academic Publishers; Springer, 2005-07)
Solvent facilitated perfusion (SFP) has been proposed as a technique to increase the delivery of chemotherapeutic agents to tumors. SFP entails direct injection of the agent into the tumor in a water-miscible organic ...
Association of genetic variation in tamoxifen-metabolizing enzymes with overall survival and recurrence of disease in breast cancer patients
(Kluwer Academic Publishers; Springer, 2005-06)
Tamoxifen has been a mainstay of adjuvant therapy for breast cancer for many years. We sought to determine if genetic variability in the tamoxifen metabolic pathway influenced overall survival in breast cancer patients ...
Intramedullary Spinal Tumors of Disordered Embryogenesis
(Kluwer Academic Publishers; Springer Science+Business Media, 2000-05)
Abnormal spinal embryogenesis is quite commonplace. While greater than 90 percent of these errors of embryogenesis leads to occult spinal dysraphism with minimal neurologic or orthopedic sequelae, there is a significant ...
RhoC Induces Differential Expression of Genes Involved in Invasion and Metastasis in MCF10A Breast Cells
(Kluwer Academic Publishers; Springer Science+Business Media, 2004-03)
Inflammatory breast cancer (IBC) is the most deadly form of breast cancer in humans presumably due to its ability to metastasize from its inception. In our laboratory, overexpression of RhoC GTPase was observed to be ...