Now showing items 1-6 of 6
Design and Testing Novel Wearable Instrumentation for Assessing Pelvic Floor Function and Exploring Continence Mechanisms
(2020)
Urinary incontinence (UI) and fecal incontinence (FI) affect 20% of North Americans, with a higher prevalence in women and the elderly. The prevention and treatment of these conditions unfortunately leaves much to be ...
Severe Illness Associated With Respiratory Viruses: Burden and Temporal Dynamics
(2020)
Acute lower respiratory tract infections (ALRI) are a substantial source of global morbidity and mortality, particularly among young children. Respiratory syncytial virus (RSV) and influenza are consistently observed to ...
The Molecular Underpinnings and Regulation of Amino Acid Pathways in Ewing sarcoma
(2022)
Ewing sarcoma is an aggressive pediatric bone and soft tissue tumor, most commonly driven by EWS-FLI1. The standard of care for Ewing sarcoma has not improved in decades, and by far the best predictor of poor prognosis is ...
Continuity and Change in Theory-of-Mind Development: A Neuroscientific Approach.
(2013)
This dissertation seeks a more comprehensive picture of the process of theory-of-mind development (an understanding that action is guided by internal mental states such as beliefs, desires, and intentions) by examining ...
Molecular Dynamics Simulation of Phase and Structural Transitions in Model Lung Surfactant Mixtures.
(2010)
Lung surfactant (LS) is a complex mixture of lipids and proteins that reduces and regulates the surface tension in the lungs, thereby decreasing the work of breathing. A thorough understanding of LS function is critical ...
Role of CHD7 in Neural Development and Maintenance.
(2011)
Normal tissue development and maintenance require precise timing and correct localization of gene expression. Several lines of evidence indicate that the chromodomain (CHD) family of proteins are critical regulators of ...