Now showing items 1-10 of 666
Inhibition of Vesicular Glutamate Uptake by Rose Bengal-Related Compounds: Structure–Activity Relationship
(Kluwer Academic Publishers-Plenum Publishers; Springer Science+Business Media, Inc., 2005-03)
Synaptic vesicular accumulation of glutamate is a vital initial step in glutamate transmission. We have previously shown that Rose Bengal, a polyhalogenated fluorescein analog, is a potent inhibitor of glutamate uptake ...
Synthetic Strategies and Parameters Involved in the Synthesis of Oligodeoxyribonucleotides According to the Phosphoramidite Method
(Wiley Periodicals, Inc.Plenum, 2000-02)
The phosphoramidite approach has had a major impact on the synthesis of oligonucleotides. This unit describes parameters that affect the performance of this method for preparing oligodeoxyribonucleotides, as well as a ...
A prediction model for colon cancer surveillance data
(Wiley Periodicals, Inc.CRC Press, Inc., 2015-08-15)
Chemical Reagents for Investigating the Major Groove of DNA
(Wiley Periodicals, Inc.Oxford University Press, 2001-07)
Chemical modification provides an inexpensive and rapid method for characterizing the structure of DNA and its association with drugs and proteins. Numerous conformation‐specific probes are available, but most investigations ...
Improving on analyses of self-reported data in a large-scale health survey by using information from an examination-based survey
(John Wiley & Sons, Ltd., 2010-02-28)
Common data sources for assessing the health of a population of interest include large-scale surveys based on interviews that often pose questions requiring a self-report, such as, ‘Has a doctor or other health professional ...
Synthesis of N2‐Substituted Deoxyguanosine Nucleosides from 2‐Fluoro‐6‐O‐(Trimethylsilylethyl)‐2′‐Deoxyinosine
(Wiley Periodicals, Inc.Aldrich Chemical Co., 2000-02)
Syntheses of N2‐substituted nucleosides have been studied for many years, primarily with ribonucleosides. However, the primary route to these compounds requires acidic conditions that are too vigorous for the acid‐labile ...
New Instrumental Variable Methods for Causal Inference.
(2016)
In observational studies, unmeasured differences between treatment groups often confound the relationship of interest. Instrumental variable (IV) methods can give consistent effect estimates in the presence of this ...
An econometric method for estimating population parameters from non‐random samples: An application to clinical case finding
(Wiley Periodicals, Inc.Centre for Tuberculosis, 2017-09)
The problem of sample selection complicates the process of drawing inference about populations. Selective sampling arises in many real world situations when agents such as doctors and customs officials search for targets ...
Modeling intra-tumor protein expression heterogeneity in tissue microarray experiments
(John Wiley & Sons, Ltd., 2008-05-20)
Tissue microarrays (TMAs) measure tumor-specific protein expression via high-density immunohistochemical staining assays. They provide a proteomic platform for validating cancer biomarkers emerging from large-scale DNA ...
Characterization of A. baumannii Environmental Survival and Biofilm Formation and the Impact on Environmental Transmission.
(2015)
Acinetobacter baumannii is a gram-negative, opportunistic pathogen primarily affecting the critically ill, causing 3% of all nosocomial-related deaths in the United States. A. baumannii’s successful environmental survival ...