Now showing items 1-10 of 13
The effect of exercise training on transverse tubules in normal, remodeled, and reverse remodeled hearts
(Wiley Subscription Services, Inc., A Wiley Company, 2011-09)
The response of transverse (T)‐tubules to exercise training in health and disease remains unclear. Therefore, we studied the effect of exercise training on the density and spacing of left ventricle cardiomyocyte T‐tubules ...
Bone marrow stromal cells stimulate an angiogenic program that requires endothelial MT1‐MMP
(Wiley Subscription Services, Inc., A Wiley Company, 2012-11)
Bone marrow‐derived stromal/stem cells (BMSCs) have recently been characterized as mediators of tissue regeneration after injury. In addition to preventing fibrosis at the wound site, BMSCs elicit an angiogenic response ...
Hypoxia induces ZEB2 in podocytes: Implications in the pathogenesis of proteinuria
(Humana PressWiley Periodicals, Inc., 2019-05)
The glomerular filtration barrier (GFB) plays a critical role in ensuing protein free urine. The integrity of the GFB is compromised during hypoxia that prevails during extreme physiological conditions. However, the mechanism ...
A High Fat Diet Increases Bone Marrow Adipose Tissue (MAT) But Does Not Alter Trabecular or Cortical Bone Mass in C57BL/6J Mice
(Wiley Periodicals, Inc., 2015-09)
High fat diet‐induced oxidative stress blocks hepatocyte nuclear factor 4α and leads to hepatic steatosis in mice
(Wiley Periodicals, Inc., 2018-06)
Amelioration of type I diabetes‐induced osteoporosis by parathyroid hormone is associated with improved osteoblast survival
(Wiley Subscription Services, Inc., A Wiley Company, 2012-04)
Type 1 diabetic osteoporosis results from impaired osteoblast activity and death. Therefore, anti‐resorptive treatments may not effectively treat bone loss in this patient population. Intermittent parathyroid hormone (PTH) ...
Morphological Effects on Expression of Growth Differentiation Factor 15 (GDF15), a Marker of Metastasis
(Wiley Periodicals, Inc., 2014-03)
Cancer cells typically demonstrate altered morphology during the various stages of disease progression as well as metastasis. While much is known about how altered cell morphology in cancer is a result of genetic regulation, ...
Kinetic properties of ASC protein aggregation in epithelial cells
(Wiley Subscription Services, Inc., A Wiley Company, 2010-03)
A poptosis-associated s peck-like protein with C ARD domain (ASC), an adaptor protein composed of caspase recruitment and pyrin domains, can efficiently self-associate to form a large spherical structure, called a speck. ...
The transcription factor osterix (SP7) regulates BMP6‐induced human osteoblast differentiation
(Wiley Subscription Services, Inc., A Wiley Company, 2012-06)
The transcription factor Osterix (Sp7) is essential for osteoblastogenesis and bone formation in mice. Genome wide association studies have demonstrated that Osterix is associated with bone mineral density in humans; ...
MAP Kinase‐Dependent RUNX2 Phosphorylation Is Necessary for Epigenetic Modification of Chromatin During Osteoblast Differentiation
(Wiley Periodicals, Inc., 2017-09)