Now showing items 1-10 of 183
A VIP-like peptide co-occurs with substance P and enkephalin in cholinergic preganglionic terminals of the avian ciliary ganglion
(Elsevier, 1987-07-09)
Using single-label and double-label immunohistochemical techniques, many of the substance P-enkephalin containing preganglionic terminals of the avian ciliary ganglion were found to also contain a VIP-like peptide. Since ...
The temporal structure of motivation: III. Identification and ecological significance of ultradian rhythms of intracranial reinforcement
(Elsevier, 1980-10)
Adult male Sprague-Dawley rats were stereotactically implanted with intracranial electrodes aimed at the anterior medial forebrain bundle, and trained to self-administer intracranial stimulation. Following 3 weeks of ...
Muscarine-sensitive voltage-dependent potassium current in cultured murine spinal cord neurons
(Elsevier, 1983-01-31)
Muscarine produced membrane depolarization and decreased membrane conductance of mouse spinal cord neurons in dissociated cell culture. When the neurons were voltage clamped, muscarine evoked inward currents which increased ...
Culturing spinal cord explants in a collagen gel
(Elsevier, 1984-08)
A new method for culturing spinal cord slices or explants is presented which entails the use of a commercially available purified collagen, Vitrogen. Vitrogen provides a stable three-dimensional matrix for culturing spinal ...
Further studies on a novel animal model of depression: Therapeutic effects of a tricyclic antidepressant
(Elsevier, 1981)
We have previously shown that rats given stress before open field testing have elevated activity in comparison with unstressed rats. This acute behavioral response may be eliminated by chronic stress and restored by ...
Susceptibility to sensitization. I. Sex differences in the enduring effects of chronic -amphetamine treatment on locomotion, stereotyped behavior and brain monoamines
(Elsevier, 1988-09-01)
There are sex differences in a number of behaviors elicited by amphetamine (AMPH). The purpose of the present experiment was to determine if there are also sex differences in the sensitization of the locomotor activity and ...
Ornithine decarboxylase activity in retinal explants of goldfish undergoing optic nerve regeneration
(Elsevier, 1981-06)
Retinal explants cultured in the presence of fetal calf serum (FCS) exhibit an increase in the activity of ornithine decarboxylase which is maximal several hours after explanation. The measured activity of this enzyme is ...
Electron microscopic demonstration of horseradish peroxidase-tetramethylbenzidine reaction product as a method for identifying sensory nerve fibers in the rat tooth pulp
(Elsevier, 1983-11-11)
The purpose of the present investigation was to determine if the horseradish peroxidase could be used as a method for labeling sensory nerve fibers (specifically, tooth pulp afferents) for detailed ultrastructural analyses. ...
Unilateral substantia nigra lesions and schedule-induced polydipsia
(Elsevier, 1986)
The present experiment investigated the effects of unilateral 6-hydroxydopamine lesions of the substantia nigra (SN) on schedule-induced polydipsia (SIP). Lesions were made in either the "dominant" or "non-dominant" ...
Animal models and human depressive disorders
(Elsevier, 1981)
Clinical depressive disorders are complex in presentation, dissimilar in origins and course, and often pleomorphic in character. An adequate understanding of their origins, biological substrates, and amenability to established ...