Now showing items 1-10 of 28
Time and dosage effects of meprobamate on visual detection
(Springer-Verlag, 1964-01)
Sixteen male subjects, 21 years and older, were run in a doubleblind own-control design under three dosages of meprobamate (400, 800 and 1600 mg) and matching placebo, to determine response curves on a visual detection ...
Differential effects of pentobarbital, ethyl alcohol, and chlorpromazine in modifying reticular facilitation of visually evoked responses in the cat
(Elsevier, 1969-01)
Cortical visually evoked responses (VER) elicited by electrical stimulation of the ipsilateral optic tract were dramatically facilitated by stimulation of the midbrain reticular formation. This facilitation depended on the ...
Some effects of muscarinic cholinergic blocking drugs on behavior and the electrocorticogram
(Springer-Verlag, 1964-03)
Results are presented for the effects of drugs with muscarinic cholinergic blocking actions, both central and peripheral (scopolamine and 1-hyoscyamine) and primarily peripheral (methyl atropine and methyl scopolamine), ...
Effects of trifluoperazine on the central nervous system of the cat
(Elsevier, 1966-01)
The effects of accumulative doses of trifluoperazine (0[middle dot]125-8 mg/kg) on the patellar and linguomandibular reflexes and segmentally evoked monosynaptic and polysynaptic spinal cord potentials were determined in ...
Effects of physostigmine on rat brain acetylcholine, acetylcholinesterase and conditioned pole jumping,
(Elsevier, 1968-03)
The present study was designed to provide evidence that the behavioral effects of physostigmine are related to inhibition of brain acetylcholinesterase (AChE). Adult male Holtzman rats were trained to pole jump to a buzzer ...
Effects of chlorpromazine on spiral cord reflex mechanisms,
(Elsevier, 1966-01)
The effects of chlorpromazine (CPZ) on the patellar reflex and segmentally evoked spinal cord potentials were determined in the high spinal and hemisectioned spinal cat preparations. CPZ in doses of 1-32 mg/kg given ...
Effects of psychoactive agents on acquisition of conditioned pole jumping in rats
(Springer-Verlag, 1965-07)
Albino rats required progressively more trials to reach a 90 percent avoidance criterion and achieved less mean total percent avoidance learning than saline injected controls following administration of increasing doses ...
Nicotine-induced eeg and behavioral arousal,
(Elsevier, 1965-11)
(-) Nicotine, in doses of 0.005-0.01 mg/kg given intravenously over 1 min, produced transient behavioral arousal and EEG activation in cats with chronic indwelling brain electrodes. The effects of nicotine were evident ...
Behavioral variables affecting the development of amphetamine tolerance
(Springer-Verlag, 1966-01)
The behavioral effects of chronic administration of d-amphetamine in rats at a dosage of 1 mg/kg were studied with baselines involving either food or shock reinforcement. Food reinforcement was assigned according to a fixed ...
Neuronal mechanisms of ketamine-induced anesthesia
(Elsevier, 1968-11)
The sites of action of ketamine (CI-581; 2-(0-chlorophenyl)-2-methylamino cyclohexamine HCl) were determined in the central nervous system using electrophysiological techniques in both acute and chronic cat experiments. ...