Now showing items 1-9 of 9
Extraction of aminoglycoside antibiotics with reverse micelles
(John Wiley & Sons, Ltd., 1996-01)
The reverse micelle system of sodium di-2-ethylhexyl phosphate was used to extract aminoglycoside antibiotics, neomycin and gentamicin. The aminoglycosides can be efficiently extracted into a reverse micelle solution, and ...
Dependence of fluorodeoxyuridine-induced cytotoxicity and megabase DNA fragment formation on S phase progression in HT29 cells
(Springer-Verlag; Springer-Verlag Berlin Heidelberg, 1996-02)
The relationship between cell cycle progression and induction of DNA double-strand breaks and cytotoxicity by exposure to fluorodeoxyuridine (FdUrd) was studied in HT29 human colon cancer cells. Fractionation of drug-treated ...
Treatment of Gaucher disease with an enzyme inhibitor
(Kluwer Academic Publishers; Chapman & Hall ; Springer Science+Business Media, 1996-04)
The hypothesis is offered predicting that Caucher patients could be treated with a drug that slows the synthesis of glucosylceramide, the lipid that accumulates in this disorder. The present therapeutic approach involves ...
Structural requirements for binding to the δ opioid receptor: Alkyl replacements at the third residue of deltorphin I
(Kluwer Academic Publishers; ESCOM Science Publishers B.V. ; Springer Science+Business Media, 1996-01)
The naturally occurring heptapeptide deltorphin I (Tyr- d -Ala-Phe-Asp-Val-Val-Gly-NH 2 ) exhibits extremely high affinity and selectivity for the δ opioid receptor. In an ongoing investigation of the features of this ...
Characterization of gangliosides from Ehrlich ascites tumour cells and their variants
(Kluwer Academic Publishers; Chapman & Hall ; Springer Science+Business Media, 1996-04)
Differences in the nature of the gangliosides present in two types of Ehrlich ascites tumour (EAT) cells, the adherent and non-adherent EAT cells, were studied. Gangliosides were isolated by DEAE Sephadex column chromatography ...
Calcification of polyurethanes implanted subdermally in rats is enhanced by calciphylaxis
(John Wiley & Sons, Inc., 1996-06)
Calcification complicates the use of the polymer polyurethane in cardiovascular implants. To date only costly experimental circulatory animal models have been useful for investigating this disease process. In this paper ...
Studies of the action of ceramide-like substances ( d - and l -PDMP) on sphingolipid glycosyltransferases and purified lactosylceramide synthase
(Kluwer Academic Publishers; Chapman & Hall ; Springer Science+Business Media, 1996-06)
We have studied the effects of D -threo-1-phenyl-2-decanoylamino-3-morpholino-1-propanol ( D -PDMP) and its L -enantiomer on glycosphingolipids in cultured normal human kidney proximal tubular cells. We found that D -PDMP ...
First-principles study of the α-Al 2 O 3 (0001)/Cu(111) interface
(Kluwer Academic Publishers; Springer Science+Business Media, 1996-12)
Adhesive energetics and interfacial electronic structures have been computed from first principles for the Cu/Al 2 O 3 interface. Recent transmission electron microscopy results of Cu grown by molecular beam epitaxy on Al ...
Preparation and characterization of high-surface-area polymer substrates for microcalorimetry
(John Wiley & Sons, Inc., 1996-05)
The preparation and characterization of high-surface-area polymeric substrates suitable for the microcalorimetry of protein adsorption are described. High-surface-area polystyrene, poly(styrene- co -butyl methacrylate) and ...