Now showing items 1-10 of 39
Computation of multilocus prior probability of autozygosity for complex inbred pedigrees
(Wiley Subscription Services, Inc., A Wiley Company, 1997)
Homozygosity mapping is a very powerful method for mapping rare recessive diseases in humans. In many applications, it is often desirable to compute prior (or unconditional) multilocus probability of autozygosity for inbred ...
Augmentation of hepatic doxorubicin extraction with extracorporeal filtration avoids the dose-dependent, nonlinear increase in AUC observed with systemic administration
(Springer-Verlag; Springer-Verlag Berlin Heidelberg, 1997-12)
Purpose : Regional therapy of primary or metastatic liver cancer with low hepatic extraction ratio drugs such as doxorubicin is constrained by development of systemic toxicity. To examine the effect of augmentation of ...
Development of Molecular Genetic Interventions for HIV Infection
(John Wiley & Sons, 1997-02)
This unit includes a set of protocols for the ex vivo transfer of genes into CD4+ T cells, to be used in the initial evaluation of genes protecting against HIV infection in gene therapy protocols. The describes isolating ...
Cell cycle of Chlorella vulgaris can deviate from the synchronous binary division model
(Kluwer Academic Publishers; Chapman and Hall ; Springer Science+Business Media, 1997-06)
Conditioned medium from high density Chlorella vugaris cultures was freeze dried extracted into ethanol. The ethanol was volatilized and the resulting powder then introduced with C. vulgaris photoautotrophic cultures which ...
Ethanol effects on self-administration of alfentanil, cocaine, and nomifensine in rhesus monkeys
(Springer-Verlag; Springer-Verlag Berlin Heidelberg, 1997-04)
A common form of polydrug use is that of cocaine and ethanol. The identification of an ethanol-cocaine combination product, cocaethylene, with properties in common with cocaine, has led to speculation that this metabolite ...
A sulfatide receptor distinct from L‐selectin is involved in lymphocyte activation
(Wiley Periodicals, Inc., 1997-12-01)
RAP1‐like binding activity in islet cells corresponds to members of the Sp1 family of transcription factors
(Wiley Periodicals, Inc., 1997-07-14)
Synthesis and characterization of precursors for group II metal aluminates
(John Wiley & Sons, Ltd., 1997-10)
Precursors to Group II metal aluminates (MAI 2 O 4 , M=Mg, Ca, Ba, Sr) are synthesized from inexpensive starting materials including Group II metal oxides/hydroxides, Al(OH) 3 , triethanolamine (TEA) and ethylene glycol, ...
GroEL provides a folding pathway with lower apparent activation energy compared to spontaneous refolding of human carbonic anhydrase II
(Wiley Periodicals, Inc., 1997-07-07)
Substitution of D-Trp 32 in NPY Destabilizes the Binding Transition State to the Y1 Receptor Site in SK-N-MC Cell Membranes
(Kluwer Academic Publishers-Plenum Publishers; Plenum Publishing Corporation ; Springer Science+Business Media, 1997-04)
The retention rate of the spin label 3-isothiocyanto methyl-2,2,5,5-tetramethyl-1-pyrrolidinyl oxyl spin label (proxyl) attached to the porcine N-acetyl-NPY peptide and the porcine N-acetyl-D-Trp 32 -NPY peptide at Lys 4 ...