Now showing items 1-10 of 40
Chemical Reagents for Investigating the Major Groove of DNA
(Wiley Periodicals, Inc.Oxford University Press, 2001-07)
Chemical modification provides an inexpensive and rapid method for characterizing the structure of DNA and its association with drugs and proteins. Numerous conformation‐specific probes are available, but most investigations ...
Application of sieve-tray air strippers to the treatment of surfactant-containing wastewaters
(Wiley Subscription Services, Inc., A Wiley Company, 2001-06)
Using sieve-tray air stripping as a means of removing contaminants from surfactant solutions was studied to determine if tray air stripping can be applied successfully to treating surfactant-containing wastewaters and, if ...
Preparation of 2′‐O‐[(Triisopropylsilyl)oxy]methyl‐protected Ribonucleosides
(Oxford University PressWiley Periodicals, Inc., 2001-12)
The [(triisopropylsilyl)oxy]methyl (TOM) group is a useful protecting group for the 2′‐OH of ribonucleosides to be used for oligoribonucleotide synthesis by the phosphoramidite method. It is completely stable to all reaction ...
Characterization of Tertiary Folding of RNA by Circular Dichroism and Urea
(Wiley Periodicals, Inc., 2001-04)
CD spectroscopy can be used to monitor RNA tertiary folding transitions that may not be observable by absorbance spectroscopy. With the use of computer‐controlled titrators, data can be acquired rapidly, and accurate ...
An adaptive treecode for computing nonbonded potential energy in classical molecular systems
(John Wiley & Sons, Inc., 2001-01-30)
A treecode algorithm is presented for rapid computation of the nonbonded potential energy in classical molecular systems. The algorithm treats a general form of pairwise particle interaction with the Coulomb and London ...
Phase II Trial of CI-980 in Patients with Disseminated Malignant Melanoma and no Prior Chemotherapy – A Southwest Oncology Group Study
(Kluwer Academic Publishers; Springer Science+Business Media, 2001-08)
Malignant melanoma is increasing infrequency at a rapid rate in the UnitedStates. Metastatic disease ischemoresistant with DTIC considered themost active single agent. CI-980 is asynthetic mitotic inhibitor that blocks ...
Unnatural Nucleosides with Unusual Base Pairing Properties
(John Wiley & Sons, 2001-07)
Synthetic modified nucleosides designed to pair in unusual ways with natural nucleobases have many potential applications in nucleic acid biochemistry. This overview lays the foundation for future protocol units on synthesis ...
Broadband dielectric spectroscopy of the inter- and intramolecular dynamics of a series of random polyester copolymers
(Springer-Verlag; Springer-Verlag Berlin Heidelberg, 2001-11)
Broadband dielectric spectroscopy (1–10 6 Hz, 183–423 K) and differential scanning calorimetry are employed to analyze the inter- and intramolecular dynamics of a series of random copolymers based on poly(ethylene ...
Multiple-Well, multiple-path unimolecular reaction systems. I. MultiWell computer program suite
(John Wiley & Sons, Inc., 2001-04)
Unimolecular reaction systems in which multiple isomers undergo simultaneous reactions via multiple decomposition reactions and multiple isomerization reactions are of fundamental interest in chemical kinetics. The computer ...
Probing DNA Structure with Hydroxyl Radicals
(Wiley Periodicals, Inc., 2001-12)
The hydroxyl radical is a useful probe for studying the shape of the surface of a DNA molecule. Using this technique, fine details of DNA structure can potentially be revealed. This unit describes how to use the hydroxyl ...