Now showing items 1-10 of 52
Role of conformational dynamics in sequence-specific autoantibody•ssDNA recognition
(Wiley Subscription Services, Inc., A Wiley Company, 2007-04-05)
11F8 is a sequence-specific monoclonal anti-ssDNA autoantibody isolated from a lupus prone mouse that forms pathogenic complexes with ssDNA, resulting in kidney damage. Prior studies show that specificity is mediated by a ...
Ring-opening polymerization of epoxy end-terminated poly(ethylene oxide) as a route to highly crosslinked materials with exceptional swelling behavior (II)
(John Wiley & Sons, Ltd., 2007-08)
Highly swellable poly(ethylene oxide) (PEO) gels were prepared by anionic ring-opening polymerization of diepoxy end-capped PEO (3400 g mol −1 ) and PEO (8000 g mol −1 ) using dianionic glycerol and glycolic acid initiators ...
Focus on function: Single molecule RNA enzymology
(Wiley Subscription Services, Inc., A Wiley Company, 2007-12-05)
The ability of RNA to catalyze chemical reactions was first demonstrated 25 years ago with the discovery that group I introns and RNase P function as RNA enzymes (ribozymes). Several additional ribozymes were subsequently ...
Minimizing the surface effect of PDMS–glass microchip on polymerase chain reaction by dynamic polymer passivation
(John Wiley & Sons, Ltd., 2007-01)
Polydimethyl siloxane (PDMS)–glass microchip has a very strong surface effect on polymerase chain reaction (PCR), leading to a very poor PCR yield. In the work reported here, practical dynamic passivation of surfaces of ...
Synthesis and Erosion Properties of PEG-Containing Polyanhydrides
(WILEY-VCH Verlag, 2007-05-10)
To tailor the erosion rate of polyanhydrides while retaining their surface erosion characteristics, new three-component polyanhydrides of sebacic acid, 1,3-bis( p -carboxyphenoxy)propane and poly(ethylene glycol) were ...
Highly Efficient, Near-Infrared Electrophosphorescence from a Pt–Metalloporphyrin Complex The authors acknowledge financial support from the U.S. Dept. of the Army, CECOM for the phase 14II SBIR program (contract no. 14W15P7T-06-C-T201), and Universal Display Corporation.
(WILEY-VCH Verlag, 2007-02-05)
No Abstract
Synthesis of the Tetraketide Lactones from the Pikromycin Biosynthetic Pathway
(WILEY-VCH Verlag, 2007-07)
Synthesis of tetraketide lactones 2 and 3 , which are likely to be produced by a model pikromycin polyketide synthase (PKS), has been investigated. The tetraketide lactones with six-membered rings, 2a and 2b , were ...
Understanding surfaces and buried interfaces of polymer materials at the molecular level using sum frequency generation vibrational spectroscopy
(John Wiley & Sons, Ltd., 2007-05)
This paper reviews recent progress in the studies on polymer surfaces/interfaces using sum frequency generation (SFG) vibrational spectroscopy. SFG theory, technique, and some experimental details have been presented. The ...
Modeling ssDNA electrophoretic migration with band broadening in an entangled or cross-linked network
(WILEY-VCH Verlag, 2007-08)
We use a coarse-grained model proposed by Graham and Larson based on the temporary network model by Schieber et al.. [1] to simulate the electrophoretic motion of ssDNA and corresponding band broadening due to dispersion. ...