Now showing items 1-4 of 4
Folylpolyglutamates as substrates and inhibitors of folate-dependent enzymes
(Elsevier, 1987)
The true intracellular substrates for folate-dependent enzymes are folylpolyglutamates. We have used measurements of the Ki values of folylpolyglutamate dead end inhibitors to assess the relative affinities of folate-dependent ...
Modulation of methylenetetrahydrofolate reductase activity by S-adenosylmethionine and by dihydrofolate and its polyglutamate analogues
(Elsevier, 1982)
Methylenetetrahydrofolate reductase catalyzes the reduction of methylenetetrahydrofolate ot methyltetrahydrofolate. This reaction commits one carbon units to the pathways of adenosylmethionine-dependent methylation in ...
Control of adenosine deaminase levels in human lymphoblasts
(Elsevier, 1982)
High levels of adenosine deaminase (ADA) activity have been associated with normal T cell differentiation and T cell disease, such as acute lymphoblastic leukemia; however, possible mechanisms controlling the level of this ...
Two cases of changes in amino acid transport activity with tissue development
(Elsevier, 1965)
During the first day of extrauterine life the liver of the guinea-pig greatly intensifies the extent of the steady-state concentration of two amino acids, one normal and one non-metabolizable. Another change with tissue ...