Now showing items 1-10 of 161
Effect of Neuropeptide Y on Natural Killer Activity of Normal Human Lymphocytes
(Elsevier, 1993-03)
The in vitro effect of neuropeptide Y (NPY) on natural killer (NK) cell activities of normal lymphocytes was investigated. NPY at 10-9 to 10-12M concentrations produced significant suppression of NK activity against K 562 ...
A dual function activity-dependent, muscle-specific enhancer from rat nicotinic acetylcholine receptor δ-subunit gene
(John Wiley & Sons, Inc., 1996-11)
Nicotinic acetylcholine receptors (nAChR) mediate communication between nerve and muscle. The expression of these receptors increases dramatically during muscle development when myoblasts are fusing into multinucleated ...
Receptor Binding Techniques
(Wiley Periodicals, Inc.Elsevier/North‐Holland Biomedical Press, 1997-09)
This overview first discusses issues relating to the selection of radioligand for receptor binding assays, including the isotopic label and considerations pertaining to the pharmacological and chemical profile of the ligand. ...
Intracellular partitioning of androgen receptor immunoreactivity in the brain of the male syrian hamster: Effects of castration and steroid replacement
(Wiley Subscription Services, Inc., A Wiley Company, 1993-07)
The effect of castration and steroid replacement on the intracellular partitioning of the androgen receptor in the brain of the male Syrian hamster was determined using immunocytochemistry. Androgen receptors were visualized ...
Lesions of the central nucleus of the amygdala I: Effects on taste reactivity, taste aversion learning and sodium appetite
(Elsevier, 1993-12-31)
Bilateral damage to the central nucleus of the amygdala (CeAX) in the rat blunts need-induced NaCl intake and abolishes daily need-free NaCl intake when measured with a two-bottle test. Such a deficit could be the result ...
Androgen receptor immunoreactivity in the male and female Syrian hamster brain
(John Wiley & Sons, Inc., 1999-06-05)
To investigate potential mechanisms for sex differences in the physiologic response to androgens, the present study compared the hormonal regulation of intracellular androgen receptor partitioning and the distribution of ...
Protease nexin-1 activity in cultured Schwann cells
(Elsevier, 1991-07-08)
We report that protease nexin-1 (PN-1), a serine protease inhibitor known to have neurite-promoting effects, is made by Schwann cells in tissue culture. Three modalities have been used to demonstrate the presence of PN-1 ...
Activity disc and cage for continuous measurement of running activity and core temperature in hamsters
(Elsevier, 1991-11)
We describe a design for the modular horizontal activity disc and tandem cages suitable for continuous monitoring of spontaneous running and of core tempertaures in golden hamsters. An acrylic disc is equipped with a short ...
Mating behavior induces selective expression of Fos protein within the chemosensory pathways of the male Syrian hamster brain
(Elsevier, 1992-08-31)
The effect of mating behavior on the expression of Fos protein was analyzed within the chemosensory pathways of the male Syrian hamster brain. Following a single mating test, the number of Fos-immunoreactive (Fos-ir) neurons ...
Chronic drug infusion into the scala tympani of the guinea pig cochlea
(Elsevier, 1992)
This research describes a unique, effective and inexpensive delivery system to provide discrete quantities of drugs on a chronic basis to the inner ear. The amount of the drug administered and specific timing of each ...