Now showing items 1-10 of 102
Inhibition of Vesicular Glutamate Uptake by Rose Bengal-Related Compounds: Structure–Activity Relationship
(Kluwer Academic Publishers-Plenum Publishers; Springer Science+Business Media, Inc., 2005-03)
Synaptic vesicular accumulation of glutamate is a vital initial step in glutamate transmission. We have previously shown that Rose Bengal, a polyhalogenated fluorescein analog, is a potent inhibitor of glutamate uptake ...
Effect of Neuropeptide Y on Natural Killer Activity of Normal Human Lymphocytes
(Elsevier, 1993-03)
The in vitro effect of neuropeptide Y (NPY) on natural killer (NK) cell activities of normal lymphocytes was investigated. NPY at 10-9 to 10-12M concentrations produced significant suppression of NK activity against K 562 ...
Ornithine decarboxylase activity in retinal explants of goldfish undergoing optic nerve regeneration
(Elsevier, 1981-06)
Retinal explants cultured in the presence of fetal calf serum (FCS) exhibit an increase in the activity of ornithine decarboxylase which is maximal several hours after explanation. The measured activity of this enzyme is ...
Developmental changes in taste responses from glossopharyngeal nerve in sheep and comparisons with chorda tympani responses
(Elsevier, 1983-12)
To learn whether there are developmental changes in salt and acid taste responses from the posterior tongue, we recorded from the glossopharyngeal nerve, which innervates taste buds in circumvallate papillae, in sheep ...
The effects of menstrual phase and nicotine abstinence on nicotine intake and on biochemical and subjective measures in women smokers: a A preliminary report
(Elsevier, 1992-11)
Nicotine intake, menstrual and smoking withdrawal symptomatology, and baseline cortisol and MHPG were assessed in nine women smokers under conditions of ad lib smoking and overnight abstinence in three menstrual phases ...
Inhibition of polyphosphoinositide phosphodiesterase by aminoglycoside antibiotics
(Kluwer Academic Publishers-Plenum Publishers; Plenum Publishing Corporation ; Springer Science+Business Media, 1985-08)
The calcium-activated phosphodiesteratic hydrolysis of 32 P-labeled phosphatidylinositol 4,5-bisphosphate and phosphatidylinositol 4-phosphate in prelabeled nerve ending membranes is inhibited by the aminoglycosides neomycin ...
Nerve growth factor increases choline acetyltransferase activity in developing basal forebrain neurons
(Elsevier, 1986-07)
Nerve growth factor (NGF) is a neuronotrophic protein. Its effects on developing peripheral sensory and sympathetic neurons have been extensively characterized, but it is not clear whether NGF plays a role during the ...
Gene expression of the insulin-like growth factors and their receptors in cultured human retinal pigment epithelial cells
(Elsevier, 1992-01)
Insulin-like growth factors I and II (IGF I and II) are polypeptides with both growth-promoting and insulin-like metabolic effects16,27. Immunoreactive IGF I is present in the retina14 and both IGF I and II are present in ...
Short-Term Adrenalectomy Increases Glucocorticoid and Mineralocorticoid Receptor mRNA in Selective Areas of the Developing Hippocampus
(Elsevier, 1993-10)
In the central nervous system, adrenal steroids bind to two different types of corticosteroid receptors: glucocorticoid (GR) or mineralocorticoid (MR). In vitro biochemical and autoradiographic techniques have been used ...
Systemic hormonal and physiological abnormalities in anxiety disorders
(Elsevier, 1988)
Among the studies of systemic hormonal and physiological abnormalities associated with anxiety disorders, the most consistent and extensive findings suggest (a) peripheral adrenergic hyperactivity (including increases in ...