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Tamoxifen Dose Escalation in Patients With Diminished CYP2D6 Activity Normalizes Endoxifen Concentrations Without Increasing Toxicity

dc.contributor.authorHertz, Daniel L.
dc.contributor.authorDeal, Allison
dc.contributor.authorIbrahim, Joseph G.
dc.contributor.authorWalko, Christine M.
dc.contributor.authorWeck, Karen E.
dc.contributor.authorAnderson, Steven
dc.contributor.authorMagrinat, Gustav
dc.contributor.authorOlajide, Oludamilola
dc.contributor.authorMoore, Susan
dc.contributor.authorRaab, Rachel
dc.contributor.authorCarrizosa, Daniel R.
dc.contributor.authorCorso, Steven
dc.contributor.authorSchwartz, Garry
dc.contributor.authorGraham, Mark
dc.contributor.authorPeppercorn, Jeffrey M.
dc.contributor.authorJones, David R.
dc.contributor.authorDesta, Zeruesenay
dc.contributor.authorFlockhart, David A.
dc.contributor.authorEvans, James P.
dc.contributor.authorMcLeod, Howard L.
dc.contributor.authorCarey, Lisa A.
dc.contributor.authorIrvin, William J.
dc.date.accessioned2017-12-15T16:47:17Z
dc.date.available2017-12-15T16:47:17Z
dc.date.issued2016-07
dc.identifier.citationHertz, Daniel L.; Deal, Allison; Ibrahim, Joseph G.; Walko, Christine M.; Weck, Karen E.; Anderson, Steven; Magrinat, Gustav; Olajide, Oludamilola; Moore, Susan; Raab, Rachel; Carrizosa, Daniel R.; Corso, Steven; Schwartz, Garry; Graham, Mark; Peppercorn, Jeffrey M.; Jones, David R.; Desta, Zeruesenay; Flockhart, David A.; Evans, James P.; McLeod, Howard L.; Carey, Lisa A.; Irvin, William J. (2016). "Tamoxifen Dose Escalation in Patients With Diminished CYP2D6 Activity Normalizes Endoxifen Concentrations Without Increasing Toxicity." The Oncologist 21(7): 795-803.
dc.identifier.issn1083-7159
dc.identifier.issn1549-490X
dc.identifier.urihttps://hdl.handle.net/2027.42/139937
dc.publisherAlphaMed Press
dc.publisherWiley Periodicals, Inc.
dc.subject.otherTamoxifen
dc.subject.otherCYP2D6
dc.subject.otherGenotype
dc.subject.otherRace
dc.subject.otherQuality of life
dc.subject.otherPharmacogenetics
dc.subject.otherToxicity
dc.subject.otherEndoxifen
dc.titleTamoxifen Dose Escalation in Patients With Diminished CYP2D6 Activity Normalizes Endoxifen Concentrations Without Increasing Toxicity
dc.typeArticleen_US
dc.rights.robotsIndexNoFollow
dc.subject.hlbsecondlevelHematology and Oncology
dc.subject.hlbtoplevelHealth Sciences
dc.description.peerreviewedPeer Reviewed
dc.contributor.affiliationumUniversity of Michigan, Ann Arbor, Michigan, USA
dc.contributor.affiliationotherPalmetto Hematology Oncology, Spartanburg, South Carolina, USA
dc.contributor.affiliationotherUniversity of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA
dc.contributor.affiliationotherMoffitt Cancer Center, Tampa, Florida, USA
dc.contributor.affiliationotherLaboratory Corporation of America, Burlington, North Carolina, USA
dc.contributor.affiliationotherMoses Cone Health Cancer Center, Greensboro, North Carolina, USA
dc.contributor.affiliationotherREX Hematology Oncology Associates, Raleigh, North Carolina, USA
dc.contributor.affiliationotherBrody School of Medicine at East Carolina University, Greenville, North Carolina, USA
dc.contributor.affiliationotherLevine Cancer Institute, Charlotte, North Carolina, USA
dc.contributor.affiliationotherLevine Cancer Institute Concord, Concord, North Carolina, USA
dc.contributor.affiliationotherWaverly Hematology/Oncology, Cary, North Carolina, USA
dc.contributor.affiliationotherDuke University, Durham, North Carolina, USA
dc.contributor.affiliationotherIndiana University, Indianapolis, Indiana, USA
dc.contributor.affiliationotherBon Secours Cancer Institute, Richmond, Virginia, USA
dc.description.bitstreamurlhttps://deepblue.lib.umich.edu/bitstream/2027.42/139937/1/onco0795-sup-0002.pdf
dc.description.bitstreamurlhttps://deepblue.lib.umich.edu/bitstream/2027.42/139937/2/onco0795-sup-0001.pdf
dc.description.bitstreamurlhttps://deepblue.lib.umich.edu/bitstream/2027.42/139937/3/onco0795.pdf
dc.identifier.doi10.1634/theoncologist.2015-0480
dc.identifier.sourceThe Oncologist
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dc.owningcollnameInterdisciplinary and Peer-Reviewed


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