Show simple item record

Genomewide association studies of suicide attempts in US soldiers

dc.contributor.authorStein, Murray B.
dc.contributor.authorWare, Erin B.
dc.contributor.authorMitchell, Colter
dc.contributor.authorChen, Chia‐yen
dc.contributor.authorBorja, Susan
dc.contributor.authorCai, Tianxi
dc.contributor.authorDempsey, Catherine L.
dc.contributor.authorFullerton, Carol S.
dc.contributor.authorGelernter, Joel
dc.contributor.authorHeeringa, Steven G.
dc.contributor.authorJain, Sonia
dc.contributor.authorKessler, Ronald C.
dc.contributor.authorNaifeh, James A.
dc.contributor.authorNock, Matthew K.
dc.contributor.authorRipke, Stephan
dc.contributor.authorSun, Xiaoying
dc.contributor.authorBeckham, Jean C.
dc.contributor.authorKimbrel, Nathan A.
dc.contributor.authorUrsano, Robert J
dc.contributor.authorSmoller, Jordan W.
dc.date.accessioned2017-12-15T16:47:47Z
dc.date.available2019-02-01T19:56:25Zen
dc.date.issued2017-12
dc.identifier.citationStein, Murray B.; Ware, Erin B.; Mitchell, Colter; Chen, Chia‐yen ; Borja, Susan; Cai, Tianxi; Dempsey, Catherine L.; Fullerton, Carol S.; Gelernter, Joel; Heeringa, Steven G.; Jain, Sonia; Kessler, Ronald C.; Naifeh, James A.; Nock, Matthew K.; Ripke, Stephan; Sun, Xiaoying; Beckham, Jean C.; Kimbrel, Nathan A.; Ursano, Robert J; Smoller, Jordan W. (2017). "Genomewide association studies of suicide attempts in US soldiers." American Journal of Medical Genetics Part B: Neuropsychiatric Genetics 174(8): 786-797.
dc.identifier.issn1552-4841
dc.identifier.issn1552-485X
dc.identifier.urihttps://hdl.handle.net/2027.42/139960
dc.publisherWiley Periodicals, Inc.
dc.subject.othersuicide attempt
dc.subject.othermilitary
dc.subject.otherrisk
dc.subject.othergenomewide association
dc.subject.othergenetics
dc.subject.othersuicide
dc.titleGenomewide association studies of suicide attempts in US soldiers
dc.typeArticleen_US
dc.rights.robotsIndexNoFollow
dc.subject.hlbsecondlevelMedicine (General)
dc.subject.hlbtoplevelHealth Sciences
dc.description.peerreviewedPeer Reviewed
dc.description.bitstreamurlhttps://deepblue.lib.umich.edu/bitstream/2027.42/139960/1/ajmgb32594.pdf
dc.description.bitstreamurlhttps://deepblue.lib.umich.edu/bitstream/2027.42/139960/2/ajmgb32594_am.pdf
dc.identifier.doi10.1002/ajmg.b.32594
dc.identifier.sourceAmerican Journal of Medical Genetics Part B: Neuropsychiatric Genetics
dc.identifier.citedreferencePosner, K., Brown, G. K., Stanley, B., Brent, D. A., Yershova, K. V., Oquendo, M. A., â ¦ Mann, J. J. ( 2011 ). The Columbiaâ Suicide Severity Rating Scale: Initial validity and internal consistency findings from three multisite studies with adolescents and adults. American Journal of Psychiatry, 168 ( 12 ), 1266 â 1277.
dc.identifier.citedreferenceGuintivano, J., Brown, T., Newcomer, A., Jones, M., Cox, O., Maher, B. S., â ¦ Kaminsky, Z. A. ( 2014 ). Identification and replication of a combined epigenetic and genetic biomarker predicting suicide and suicidal behaviors. American Journal of Psychiatry, 171 ( 12 ), 1287 â 1296.
dc.identifier.citedreferenceGuran, T., Buonocore, F., Saka, N., Ozbek, M. N., Aycan, Z., Bereket, A., â ¦ Achermann, J. C. ( 2016 ). Rare causes of primary adrenal insufficiency: Genetic and clinical characterization of a large nationwide cohort. Journal of Clinical Endocrinology & Metabolism, 101 ( 1 ), 284 â 292.
dc.identifier.citedreferenceJackson, D. S., Ramachandrappa, S., Clark, A. J., & Chan, L. F. ( 2015 ). Melanocortin receptor accessory proteins in adrenal disease and obesity. Frontiers in Neuroscience, 9, 213.
dc.identifier.citedreferenceKaminsky, Z., Wilcox, H. C., Eaton, W. W., Van Eck, K., Kilaru, V., Jovanovic, T., â ¦ Smith, A. K. ( 2015 ). Epigenetic and genetic variation at SKA2 predict suicidal behavior and postâ traumatic stress disorder. Translational Psychiatry, 5, e627.
dc.identifier.citedreferenceLeardMann, C. A., Powell, T. M., Smith, T. C., Bell, M. R., Smith, B., Boyko, E. J., â ¦ Hoge, C. W. ( 2013 ). Risk factors associated with suicide in current and former US military personnel. JAMA, 310 ( 5 ), 496 â 506.
dc.identifier.citedreferenceLeon, A., Omri, B., Gely, A., Klein, C., & Crisanti, P. ( 2006 ). QN1/KIAA1009: A new essential protein for chromosome segregation and mitotic spindle assembly. Oncogene, 25 ( 13 ), 1887 â 1895.
dc.identifier.citedreferenceMenke, A., Domschke, K., Czamara, D., Klengel, T., Hennings, J., Lucae, S., â ¦ Binder, E. B. ( 2012 ). Genomeâ wide association study of antidepressant treatmentâ emergent suicidal ideation. Neuropsychopharmacology, 37 ( 3 ), 797 â 807.
dc.identifier.citedreferenceMirkovic, B., Laurent, C., Podlipski, M. A., Frebourg, T., Cohen, D., & Gerardin, P. ( 2016 ). Genetic association studies of suicidal behavior: A review of the past 10 years, progress, limitations, and future directions. Frontiers in Psychiatry, 7, 158.
dc.identifier.citedreferenceMullins, N., Perroud, N., Uher, R., Butler, A. W., Cohenâ Woods, S., Rivera, M., â ¦ Lewis, C. M. ( 2014 ). Genetic relationships between suicide attempts, suicidal ideation and major psychiatric disorders: A genomeâ wide association and polygenic scoring study. American Journal of Medical Genetics Part B: Neuropsychiatric Genetics, 165B ( 5 ), 428 â 437.
dc.identifier.citedreferenceNeale, B. M., Medland, S. E., Ripke, S., Asherson, P., Franke, B., Lesch, K. P., â ¦ Psychiatric GCAS. ( 2010 ). Metaâ analysis of genomeâ wide association studies of attentionâ deficit/hyperactivity disorder. Journal of the American Academy of Child and Adolescent Psychiatry, 49 ( 9 ), 884 â 897.
dc.identifier.citedreferenceNiculescu, A. B., Levey, D., Leâ Niculescu, H., Niculescu, E., Kurian, S. M., & Salomon, D. ( 2015 ). Psychiatric blood biomarkers: Avoiding jumping to premature negative or positive conclusions. Molecular Psychiatry, 20 ( 3 ), 286 â 288.
dc.identifier.citedreferenceNiculescu, A. B., Levey, D. F., Phalen, P. L., Leâ Niculescu, H., Dainton, H. D., Jain, N., â ¦ Salomon, D. R. ( 2015 ). Understanding and predicting suicidality using a combined genomic and clinical risk assessment approach. Molecular Psychiatry, 20 ( 11 ), 1266 â 1285.
dc.identifier.citedreferenceNock, M. K., Deming, C. A., Fullerton, C. S., Gilman, S. E., Goldenberg, M., Kessler, R. C., â ¦ Ursano, R. J. ( 2013 ). Suicide among soldiers: A review of psychosocial risk and protective factors. Psychiatry, 76 ( 2 ), 97 â 125.
dc.identifier.citedreferenceNock, M. K., Stein, M. B., Heeringa, S. G., Ursano, R. J., Colpe, L. J., Fullerton, C. S., â ¦ Kessler, R. C. ( 2014 ). Prevalence and correlates of suicidal behavior among soldiers: Results from the army study to assess risk and resilience in servicemembers (Army STARRS). JAMA Psychiatry, 71 ( 5 ), 514 â 522.
dc.identifier.citedreferenceNovoselova, T. V., Jackson, D., Campbell, D. C., Clark, A. J., & Chan, L. F. ( 2013 ). Melanocortin receptor accessory proteins in adrenal gland physiology and beyond. Journal of Endocrinology, 217 ( 1 ), R1 â 11.
dc.identifier.citedreferenceOquendo, M. A., Galfalvy, H., Sullivan, G. M., Miller, J. M., Milak, M. M., Sublette, M. E., â ¦ Mann, J. J. ( 2016 ). Positron emission tomographic imaging of the serotonergic system and prediction of risk and lethality of future suicidal behavior. JAMA Psychiatry, 73 ( 10 ), 1048 â 1055.
dc.identifier.citedreferenceOquendo, M. A., Sullivan, G. M., Sudol, K., Bacaâ Garcia, E., Stanley, B. H., Sublette, M. E., & Mann, J. J. ( 2014 ). Toward a biosignature for suicide. American Journal of Psychiatry, 171 ( 12 ), 1259 â 1277.
dc.identifier.citedreferencePerlis, R. H., Huang, J., Purcell, S., Fava, M., Rush, A. J., Sullivan, P. F., â ¦ Smoller, J. W. ( 2010 ). Genomeâ wide association study of suicide attempts in mood disorder patients. American Journal of Psychiatry, 167 ( 12 ), 1499 â 1507.
dc.identifier.citedreferencePerroud, N., Uher, R., Ng, M. Y., Guipponi, M., Hauser, J., Henigsberg, N., â ¦ McGuffin, P. ( 2012 ). Genomeâ wide association study of increasing suicidal ideation during antidepressant treatment in the GENDEP project. The Pharmacogenomics Journal, 12 ( 1 ), 68 â 77.
dc.identifier.citedreferencePsychiatric GWAS Consortium Bipolar Disorder Working Group. ( 2011 ). Largeâ scale genomeâ wide association analysis of bipolar disorder identifies a new susceptibility locus near ODZ4. Nature Genetics, 43 ( 10 ), 977 â 983.
dc.identifier.citedreferenceRamsawh, H. J., Fullerton, C. S., Mash, H. B., Ng, T. H., Kessler, R. C., Stein, M. B., & Ursano, R. J. ( 2014 ). Risk for suicidal behaviors associated with PTSD, depression, and their comorbidity in the U.S. Army. Journal of Affective Disorders, 161, 116 â 122.
dc.identifier.citedreferenceRipke, S., Wray, N. R., Lewis, C. M., Hamilton, S. P., Weissman, M. M., Breen, G., â ¦ Sullivan, P. F. ( 2013 ). A megaâ analysis of genomeâ wide association studies for major depressive disorder. Molecular Psychiatry, 18 ( 4 ), 497 â 511.
dc.identifier.citedreferenceSchizophrenia Working Group of the Psychiatric Genomics Consortium. ( 2014 ). Biological insights from 108 schizophreniaâ associated genetic loci. Nature, 511 ( 7510 ), 421 â 427.
dc.identifier.citedreferenceSchosser, A., Butler, A. W., Ising, M., Perroud, N., Uher, R., Ng, M. Y., â ¦ Lewis, C. M. ( 2011 ). Genomewide association scan of suicidal thoughts and behaviour in major depression. PLoS ONE, 6 ( 7 ), e20690.
dc.identifier.citedreferenceSokolowski, M., Wasserman, J., & Wasserman, D. ( 2014 ). Genomeâ wide association studies of suicidal behaviors: A review. European Neuropsychopharmacology, 24 ( 10 ), 1567 â 1577.
dc.identifier.citedreferenceSokolowski, M., Wasserman, J., & Wasserman, D. ( 2016 ). Polygenic associations of neurodevelopmental genes in suicide attempt. Molecular Psychiatry, 21 ( 10 ), 1381 â 1390.
dc.identifier.citedreferenceStein, M. B., Chen, C. Y., Ursano, R. J., Cai, T., Gelernter, J., Heeringa, S. G., â ¦ Army Study to Assess Risk and Resilience in Servicemembers Collaborators. ( 2016 ). Genomeâ wide association studies of posttraumatic stress disorder in 2 cohorts of US army soldiers. JAMA Psychiatry, 73 ( 7 ), 695 â 704.
dc.identifier.citedreferenceSudol, K., & Mann, J. J. ( 2017 ). Biomarkers of suicide attempt behavior: Towards a biological model of risk. Current Psychiatry Reports, 19 ( 6 ), 31.
dc.identifier.citedreferenceTidemalm, D., Runeson, B., Waern, M., Frisell, T., Carlstrom, E., Lichtenstein, P., & Langstrom, N. ( 2011 ). Familial clustering of suicide risk: A total population study of 11.4 million individuals. Psychological Medicine, 41 ( 12 ), 2527 â 2534.
dc.identifier.citedreferenceTurecki, G. ( 2014 ). The molecular bases of the suicidal brain. Nature Reviews Neuroscience, 15 ( 12 ), 802 â 816.
dc.identifier.citedreferenceUrsano, R. J. ( 2013 ). Suicide: A national health challenge, an army health threat. Psychiatry, 76 ( 2 ), 95 â 96.
dc.identifier.citedreferenceUrsano, R. J., Colpe, L. J., Heeringa, S. G., Kessler, R. C., Schoenbaum, M., Stein, M. B., & Army, S. C. ( 2014 ). The Army study to assess risk and resilience in servicemembers (Army STARRS). Psychiatry, 77 ( 2 ), 107 â 119.
dc.identifier.citedreferenceUrsano, R. J., Kessler, R. C., Stein, M. B., Naifeh, J. A., Aliaga, P. A., Fullerton, C. S., â ¦ Army Study to Assess Risk and Resilience in Servicemembers C. ( 2015 ). Suicide attempts in the US army during the wars in Afghanistan and Iraq, 2004 to 2009. JAMA Psychiatry, 72 ( 9 ), 917 â 926.
dc.identifier.citedreferenceWang, W. J., Tay, H. G., Soni, R., Perumal, G. S., Goll, M. G., Macaluso, F. P., â ¦ Tsou, M. F. ( 2013 ). CEP162 is an axonemeâ recognition protein promoting ciliary transition zone assembly at the cilia base. Nature Cell Biology, 15 ( 6 ), 591 â 601.
dc.identifier.citedreferenceWhiteford, H. A., Degenhardt, L., Rehm, J., Baxter, A. J., Ferrari, A. J., Erskine, H. E., â ¦ Vos, T. ( 2013 ). Global burden of disease attributable to mental and substance use disorders: Findings from the Global Burden of Disease Study 2010. Lancet, 382 ( 9904 ), 1575 â 1586.
dc.identifier.citedreferenceWillour, V. L., Seifuddin, F., Mahon, P. B., Jancic, D., Pirooznia, M., Steele, J., â ¦ Potash, J. B. ( 2012 ). A genomeâ wide association study of attempted suicide. Molecular Psychiatry, 17 ( 4 ), 433 â 444.
dc.identifier.citedreferenceYin, H., Pantazatos, S. P., Galfalvy, H., Huang, Y. Y., Rosoklija, G. B., Dwork, A. J., â ¦ Mann, J. J. ( 2016 ). A pilot integrative genomics study of GABA and glutamate neurotransmitter systems in suicide, suicidal behavior, and major depressive disorder. American Journal of Medical Genetics Part B: Neuropsychiatric Genetics, 171B ( 3 ), 414 â 426.
dc.identifier.citedreferenceAfifi, T. O., Taillieu, T., Zamorski, M. A., Turner, S., Cheung, K., & Sareen, J. ( 2016 ). Association of child abuse exposure with suicidal ideation, suicide plans, and suicide attempts in military personnel and the general population in Canada. JAMA Psychiatry, 73 ( 3 ), 229 â 238.
dc.identifier.citedreferenceAnglemyer, A., Miller, M. L., Buttrey, S., & Whitaker, L. ( 2016 ). Suicide rates and methods in active duty military personnel, 2005 to 2011: A cohort study. Annals of Internal Medicine, 165 ( 3 ), 167 â 174.
dc.identifier.citedreferenceArmed Forces Health Surveillance Center. ( 2014 ). Surveillance snapshot: Manner and cause of death, active component, U.S. Armed Forces, 1998â 2013. p 21.
dc.identifier.citedreferenceAsai, M., Ramachandrappa, S., Joachim, M., Shen, Y., Zhang, R., Nuthalapati, N., â ¦ Majzoub, J. A. ( 2013 ). Loss of function of the melanocortin 2 receptor accessory protein 2 is associated with mammalian obesity. Science, 341 ( 6143 ), 275 â 278.
dc.identifier.citedreferenceAshleyâ Koch, A. E., Garrett, M. E., Gibson, J., Liu, Y., Dennis, M. F., Kimbrel, N. A., â ¦ Hauser, M. A. ( 2015 ). Genomeâ wide association study of posttraumatic stress disorder in a cohort of Iraqâ Afghanistan era veterans. Journal of Affective Disorders, 184, 225 â 234.
dc.identifier.citedreferenceChan, L. F., Webb, T. R., Chung, T. T., Meimaridou, E., Cooray, S. N., Guasti, L., â ¦ Clark, A. J. ( 2009 ). MRAP and MRAP2 are bidirectional regulators of the melanocortin receptor family. Proceedings of the National Academy of Sciences of the United States of America 106 ( 15 ), 6146 â 6151.
dc.identifier.citedreferenceChang, C. C., Chow, C. C., Tellier, L. C., Vattikuti, S., Purcell, S. M., & Lee, J. J. ( 2015 ). Secondâ generation PLINK: Rising to the challenge of larger and richer datasets. Gigascience, 4, 7.
dc.identifier.citedreferenceCrossâ Disorder Group of the Psychiatric Genomics Consortium, Lee, S. H., Ripke, S., Neale, B. M., Faraone, S. V., â ¦ International Inflammatory Bowel Disease Genetics C. ( 2013 ). Genetic relationship between five psychiatric disorders estimated from genomeâ wide SNPs. Nature Genetics, 45 ( 9 ), 984 â 994.
dc.identifier.citedreferencede Leeuw, C. A., Mooij, J. M., Heskes, T., & Posthuma, D. ( 2015 ). MAGMA: Generalized geneâ set analysis of GWAS data. PLOS Computational Biology, 11 ( 4 ), e1004219.
dc.identifier.citedreferenceDores, R. M., Liang, L., Davis, P., Thomas, A. L., & Petko, B. ( 2016 ). 60 YEARS OF POMC: Melanocortin receptors: Evolution of ligand selectivity for melanocortin peptides. Journal of Molecular Endocrinology, 56 ( 4 ), T119 â T133.
dc.identifier.citedreferenceEngel, C. C. ( 2013 ). Suicide, mental disorders, and the US military: Time to focus on mental health service delivery. JAMA, 310 ( 5 ), 484 â 485.
dc.identifier.citedreferenceGalfalvy, H., Haghighi, F., Hodgkinson, C., Goldman, D., Oquendo, M. A., Burke, A., â ¦ Mann, J. J. ( 2015 ). A genomeâ wide association study of suicidal behavior. AAmerican Journal of Medical Genetics Part B: Neuropsychiatric Genetics, 168 ( 7 ), 557 â 563.
dc.identifier.citedreferenceGelernter, J. ( 2015 ). Genetics of complex traits in psychiatry. Biological Psychiatry, 77 ( 1 ), 36 â 42.
dc.identifier.citedreferenceGould, T. D., Georgiou, P., Brenner, L. A., Brundin, L., Can, A., Courtet, P., â ¦ Postolache, T. T. ( 2017 ). Animal models to improve our understanding and treatment of suicidal behavior. Translational Psychiatry, 7 ( 4 ), e1092.
dc.owningcollnameInterdisciplinary and Peer-Reviewed


Files in this item

Show simple item record

Remediation of Harmful Language

The University of Michigan Library aims to describe library materials in a way that respects the people and communities who create, use, and are represented in our collections. Report harmful or offensive language in catalog records, finding aids, or elsewhere in our collections anonymously through our metadata feedback form. More information at Remediation of Harmful Language.

Accessibility

If you are unable to use this file in its current format, please select the Contact Us link and we can modify it to make it more accessible to you.