Pregnancy Outcomes After Endometrioma Excision in Patients Undergoing In Vitro Fertilization and Embryo Transfer: A Historical Cohort Study
dc.contributor.author | Raju, Rubin | |
dc.contributor.author | Agarwal, Komal | |
dc.contributor.author | Abuzeid, Omar | |
dc.contributor.author | Joseph, Salem | |
dc.contributor.author | Ashraf, Mohammed | |
dc.contributor.author | Abuzeid, Mostafa I. | |
dc.date.accessioned | 2017-12-19T21:14:08Z | |
dc.date.available | 2017-12-19T21:14:08Z | |
dc.date.issued | 2015-06-18 | |
dc.identifier.citation | Raju, Rubin; Agarwal, Komal; Abuzeid, Omar; Joseph, Salem; Ashraf, Mohammed; Abuzeid, Mostafa I. (2015). "Pregnancy Outcomes After Endometrioma Excision in Patients Undergoing In Vitro Fertilization and Embryo Transfer: A Historical Cohort Study." Journal of Gynecologic Surgery 31 (4): 214-219. | |
dc.identifier.issn | 1042-4067 | |
dc.identifier.uri | https://hdl.handle.net/2027.42/140100 | |
dc.description.abstract | Objective: The objective of the study was to examine the effect of endometrioma excision on pregnancy outcomes in women with advanced-stage endometriosis who underwent in vitro fertilization and embryo transfer (IVF-ET). Design: This is a historical cohort study. Materials and Methods: We compared the pregnancy outcomes of 141 women undergoing IVF-ET. The study group consisted of 25 patients who had stage III/IV endometriosis and endometrioma excision (group 1). The control groups included 40 patients who had stage III/IV endometriosis, but no endometrioma and who underwent ovariolysis (group 2) and 76 patients with tubal factors infertility who underwent tubal surgery (group 3). After surgery up to two IVF-ET cycles in each group were analyzed. Results: Our study showed that the mean total dose of gonadotropin administered in IVF-ET cycle I was higher in group 1 compared with groups 2 and 3 (p=0.03). Otherwise, there was no significant difference in the ovarian responses among the three groups. There was a statistically significant increase in clinical pregnancy rate per cycle in the endometrioma group (69.7%) versus the ovariolysis group (48.1%) and tubal factor group (48.0%). However, there was no significant difference in delivery rate per cycle among the three groups. There was a statistically significant higher miscarriage rate in the endometrioma group (39.1%) compared with the ovariolysis group (11.5%) and tubal factor group (14.3%). Conclusion: In conclusion, our study suggests that endometrioma excision surgery does not compromise the overall ovarian reserve or pregnancy outcomes after IVF-ET. (J GYNECOL SURG 31:214) | |
dc.publisher | Mary Ann Liebert, Inc., publishers | |
dc.title | Pregnancy Outcomes After Endometrioma Excision in Patients Undergoing In Vitro Fertilization and Embryo Transfer: A Historical Cohort Study | |
dc.type | Article | |
dc.subject.hlbtoplevel | Health Sciences | |
dc.description.peerreviewed | Peer Reviewed | |
dc.description.bitstreamurl | https://deepblue.lib.umich.edu/bitstream/2027.42/140100/1/gyn.2015.0013.pdf | |
dc.identifier.doi | 10.1089/gyn.2015.0013 | |
dc.identifier.source | Journal of Gynecologic Surgery | |
dc.owningcollname | Interdisciplinary and Peer-Reviewed |
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