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Genomeâ Wide Study of Subcutaneous and Visceral Adipose Tissue Reveals Novel Sexâ Specific Adiposity Loci in Mexican Americans

dc.contributor.authorGao, Chuan
dc.contributor.authorLangefeld, Carl D.
dc.contributor.authorZiegler, Julie T.
dc.contributor.authorTaylor, Kent D.
dc.contributor.authorNorris, Jill M.
dc.contributor.authorChen, Yii‐der I.
dc.contributor.authorHellwege, Jacklyn N.
dc.contributor.authorGuo, Xiuqing
dc.contributor.authorAllison, Matthew A.
dc.contributor.authorSpeliotes, Elizabeth K.
dc.contributor.authorRotter, Jerome I.
dc.contributor.authorBowden, Donald W.
dc.contributor.authorWagenknecht, Lynne E.
dc.contributor.authorPalmer, Nicholette D.
dc.date.accessioned2018-02-05T16:31:08Z
dc.date.available2019-03-01T21:00:17Zen
dc.date.issued2018-01
dc.identifier.citationGao, Chuan; Langefeld, Carl D.; Ziegler, Julie T.; Taylor, Kent D.; Norris, Jill M.; Chen, Yii‐der I. ; Hellwege, Jacklyn N.; Guo, Xiuqing; Allison, Matthew A.; Speliotes, Elizabeth K.; Rotter, Jerome I.; Bowden, Donald W.; Wagenknecht, Lynne E.; Palmer, Nicholette D. (2018). "Genomeâ Wide Study of Subcutaneous and Visceral Adipose Tissue Reveals Novel Sexâ Specific Adiposity Loci in Mexican Americans." Obesity 26(1): 202-212.
dc.identifier.issn1930-7381
dc.identifier.issn1930-739X
dc.identifier.urihttps://hdl.handle.net/2027.42/141319
dc.publisherWiley Periodicals, Inc.
dc.titleGenomeâ Wide Study of Subcutaneous and Visceral Adipose Tissue Reveals Novel Sexâ Specific Adiposity Loci in Mexican Americans
dc.typeArticleen_US
dc.rights.robotsIndexNoFollow
dc.subject.hlbsecondlevelEndocrinology
dc.subject.hlbtoplevelHealth Sciences
dc.description.peerreviewedPeer Reviewed
dc.description.bitstreamurlhttps://deepblue.lib.umich.edu/bitstream/2027.42/141319/1/oby22074.pdf
dc.description.bitstreamurlhttps://deepblue.lib.umich.edu/bitstream/2027.42/141319/2/oby22074_am.pdf
dc.identifier.doi10.1002/oby.22074
dc.identifier.sourceObesity
dc.identifier.citedreferenceBerndt SI, Gustafsson S, Magi R, et al. Genomeâ wide metaâ analysis identifies 11 new loci for anthropometric traits and provides insights into genetic architecture. Nat Genet 2013; 45: 501 â 512.
dc.identifier.citedreferenceAlexander DH, Novembre J, Lange K. Fast modelâ based estimation of ancestry in unrelated individuals. Genome Res 2009; 19: 1655 â 1664.
dc.identifier.citedreferenceAlmasy L, Blangero J. Multipoint quantitativeâ trait linkage analysis in general pedigrees. Am J Hum Genet 1998; 62: 1198 â 1211.
dc.identifier.citedreferenceBild DE, Bluemke DA, Burke GL, et al. Multiâ Ethnic Study of Atherosclerosis: objectives and design. Am J Epidemiol 2002; 156: 871 â 881.
dc.identifier.citedreferenceShah RV, Murthy VL, Abbasi SA, et al. Visceral adiposity and the risk of metabolic syndrome across body mass index: the MESA Study. JACC Cardiovasc Imaging 2014; 7: 1221 â 1235.
dc.identifier.citedreferenceSung YJ, Perusse L, Sarzynski MA, et al. Genomeâ wide association studies suggest sexâ specific loci associated with abdominal and visceral fat. Int J Obes (Lond) 2016; 40: 662 â 674.
dc.identifier.citedreferenceChu AY, Deng X, Fisher VA, et al. Multiethnic genomeâ wide metaâ analysis of ectopic fat depots identifies loci associated with adipocyte development and differentiation. Nat Genet 2017; 49: 125 â 130.
dc.identifier.citedreferenceTatusova T, Ciufo S, Fedorov B, O’Neill K, Tolstoy I. RefSeq microbial genomes database: new representation and annotation strategy. Nucleic Acids Res 2014; 42: D553 â D559.
dc.identifier.citedreferenceAwata T, Yamashita H, Kurihara S, et al. A lowâ frequency GLIS3 variant associated with resistance to Japanese type 1 diabetes. Biochem Biophys Res Commun 2013; 437: 521 â 525.
dc.identifier.citedreferenceRees SD, Hydrie MZ, O’Hare JP, et al. Effects of 16 genetic variants on fasting glucose and type 2 diabetes in South Asians: ADCY5 and GLIS3 variants may predispose to type 2 diabetes. PLoS One 2011; 6: e24710. doi: 10.1371/journal.pone.0024710
dc.identifier.citedreferenceNogueira TC, Paula FM, Villate O, et al. GLIS3, a susceptibility gene for type 1 and type 2 diabetes, modulates pancreatic beta cell apoptosis via regulation of a splice variant of the BH3â only protein Bim. PLoS Genet 2013; 9: e1003532. doi: 10.1371/journal.pgen.1003532
dc.identifier.citedreferenceLisinski I, Matsumoto H, Yver DR, Schurmann A, Cushman SW, Alâ Hasani H. Identification and characterization of p49/STRAP as a novel GLUT4â binding protein. Biochem Biophys Res Commun 2006; 344: 1179 â 1185.
dc.identifier.citedreferenceZheng B, Ma YC, Ostrom RS, et al. RGSâ PX1, a GAP for GalphaS and sorting nexin in vesicular trafficking. Science 2001; 294: 1939 â 1942.
dc.identifier.citedreferenceRandall JC, Winkler TW, Kutalik Z, et al. Sexâ stratified genomeâ wide association studies including 270,000 individuals show sexual dimorphism in genetic loci for anthropometric traits. PLoS Genet 2013; 9: e1003500. doi: 10.1371/journal.pgen.1003500
dc.identifier.citedreferenceScully T. Public health: society at large. Nature 2014; 508: S50 â S51.
dc.identifier.citedreferenceWiller CJ, Schmidt EM, Sengupta S, et al. Discovery and refinement of loci associated with lipid levels. Nat Genet 2013; 45: 1274 â 1283.
dc.identifier.citedreferenceComuzzie AG, Cole SA, Laston SL, et al. Novel genetic loci identified for the pathophysiology of childhood obesity in the Hispanic population. PLoS One 2012; 7: e51954. doi: 10.1371/journal.pone.0051954
dc.identifier.citedreferenceDichgans M, Malik R, Konig IR, et al. Shared genetic susceptibility to ischemic stroke and coronary artery disease: a genomeâ wide analysis of common variants. Stroke 2014; 45: 24 â 36.
dc.identifier.citedreferenceOvergaard MT, Boldt HB, Laursen LS, Sottrupâ Jensen L, Conover CA, Oxvig C. Pregnancyâ associated plasma proteinâ A2 (PAPPâ A2), a novel insulinâ like growth factorâ binding proteinâ 5 proteinase. J Biol Chem 2001; 276: 21849 â 21853.
dc.identifier.citedreferenceJia J, Li L, Zhao Q, et al. Association of a single nucleotide polymorphism in pregnancyâ associated plasma proteinâ A2 with developmental dysplasia of the hip: a caseâ control study. Osteoarthritis Cartilage 2012; 20: 60 â 63.
dc.identifier.citedreferenceBuimer M, Keijser R, Jebbink JM, et al. Seven placental transcripts characterize HELLPâ syndrome. Placenta 2008; 29: 444 â 453.
dc.identifier.citedreferenceLango Allen H, Estrada K, Lettre G, et al. Hundreds of variants clustered in genomic loci and biological pathways affect human height. Nature 2010; 467: 832 â 838.
dc.identifier.citedreferenceChristians JK, de Zwaan DR, Fung SH. Pregnancy associated plasma protein A2 (PAPPâ A2) affects bone size and shape and contributes to natural variation in postnatal growth in mice. PLoS One 2013; 8: e56260. doi: 10.1371/journal.pone.0056260
dc.identifier.citedreferenceHu Z, Shi Y, Mo X, et al. A genomeâ wide association study identifies two risk loci for congenital heart malformations in Han Chinese populations. Nat Genet 2013; 45: 818 â 821.
dc.identifier.citedreferenceDikoglu E, Simsekâ Kiper PO, Utine GE, et al. Homozygosity for a novel truncating mutation confirms TBX15 deficiency as the cause of Cousin syndrome. Am J Med Genet A 2013; 161A: 3161 â 3165.
dc.identifier.citedreferenceHeid IM, Jackson AU, Randall JC, et al. Metaâ analysis identifies 13 new loci associated with waistâ hip ratio and reveals sexual dimorphism in the genetic basis of fat distribution. Nat Genet 2010; 42: 949 â 960.
dc.identifier.citedreferenceCarithers LJ, Moore HM. The Genotypeâ Tissue Expression (GTEx) Project. Biopreserv Biobank 2015; 13: 307 â 308.
dc.identifier.citedreferenceNarkiewicz K. Obesity and hypertensionâ â the issue is more complex than we thought. Nephrol Dial Transplant 2005; 21: 264 â 267.
dc.identifier.citedreferenceFrayling TM, Timpson NJ, Weedon MN, et al. A common variant in the fto gene is associated with body mass index and predisposes to childhood and adult obesity. Science 2007; 316: 889 â 894.
dc.identifier.citedreferenceWajchenberg BL. Subcutaneous and visceral adipose tissue: their relation to the metabolic syndrome. Endocr Rev 2000; 21: 697 â 738.
dc.identifier.citedreferenceCohen P, Levy JD, Zhang Y, et al. Ablation of PRDM16 and beige adipose causes metabolic dysfunction and a subcutaneous to visceral fat switch. Cell 2014; 156: 304 â 316.
dc.identifier.citedreferenceTaylor RW, Jones IE, Williams SM, Goulding A. Evaluation of waist circumference, waistâ toâ hip ratio, and the conicity index as screening tools for high trunk fat mass, as measured by dualâ energy Xâ ray absorptiometry, in children aged 3â 19 y. Am J Clin Nutr 2000; 72: 490 â 495.
dc.identifier.citedreferenceNorris JM, Langefeld CD, Scherzinger AL, et al. Quantitative trait loci for abdominal fat and BMI in Hispanicâ Americans and Africanâ Americans: the IRAS Family Study. Int J Obes (Lond) 2005; 29: 67 â 77.
dc.identifier.citedreferenceBlaak E. Gender differences in fat metabolism. Curr Opin Clin Nutr Metab Care 2001; 4: 499 â 502.
dc.identifier.citedreferenceFox CS, Liu Y, White CC, et al. Genomeâ wide association for abdominal subcutaneous and visceral adipose reveals a novel locus for visceral fat in women. PLoS Genet 2012; 8: e1002695. doi: 10.1371/journal.pgen.1002695
dc.identifier.citedreferenceZillikens MC, Yazdanpanah M, Pardo LM, et al. Sexâ specific genetic effects influence variation in body composition. Diabetologia 2008; 51: 2233 â 2241.
dc.identifier.citedreferenceShungin D, Winkler TW, Croteauâ Chonka DC, et al. New genetic loci link adipose and insulin biology to body fat distribution. Nature 2015; 518: 187 â 196.
dc.identifier.citedreferenceHenkin L, Bergman RN, Bowden DW, et al. Genetic epidemiology of insulin resistance and visceral adiposity. The IRAS Family Study design and methods. Ann Epidemiol 2003; 13: 211 â 217.
dc.identifier.citedreferenceGao C, Wang N, Guo X, et al. A comprehensive analysis of common and rare variants to identify adiposity loci in Hispanic Americans: the IRAS Family Study (IRASFS). PLoS One 2015; 10: e0134649. doi: 10.1371/journal.pone.0134649
dc.identifier.citedreferenceGao C, Hsu FC, Dimitrov LM, et al. A genomeâ wide linkage and association analysis of imputed insertions and deletions with cardiometabolic phenotypes in Mexican Americans: the Insulin Resistance Atherosclerosis Family Study. Genet Epidemiol 2017; 41: 353 â 362.
dc.identifier.citedreferenceGoodarzi MO, Langefeld CD, Xiang AH, et al. Insulin sensitivity and insulin clearance are heritable and have strong genetic correlation in Mexican Americans. Obesity (Silver Spring) 2014; 22: 1157 â 1164.
dc.identifier.citedreferenceHowie BN, Donnelly P, Marchini J. A flexible and accurate genotype imputation method for the next generation of genomeâ wide association studies. PLoS Genet 2009; 5: e1000529. doi: 10.1371/journal.pgen.1000529
dc.owningcollnameInterdisciplinary and Peer-Reviewed


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