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Use of Chemical Modification To Elucidate RNA Folding Pathways
dc.contributor.authorMathews, David H.
dc.contributor.authorTurner, Douglas H.
dc.date.accessioned2018-05-15T20:12:25Z
dc.date.available2018-05-15T20:12:25Z
dc.date.issued2002-06
dc.identifier.citationMathews, David H.; Turner, Douglas H. (2002). "Use of Chemical Modification To Elucidate RNA Folding Pathways." Current Protocols in Nucleic Acid Chemistry 9(1): 11.9.1-11.9.4.
dc.identifier.issn1934-9270
dc.identifier.issn1934-9289
dc.identifier.urihttps://hdl.handle.net/2027.42/143596
dc.description.abstractAs discussed in this overview, chemical modification is sensitive to the accessibility of a nucleotide to the solvent, and many nucleotides become less accessible as an RNA folds into its structured form. Chemical modification reagents are therefore suitable for following RNA folding, and can be used to study the kinetics of structure formation on time scales ranging from minutes to hours.
dc.publisherWiley Periodicals, Inc.
dc.titleUse of Chemical Modification To Elucidate RNA Folding Pathways
dc.typeArticleen_US
dc.rights.robotsIndexNoFollow
dc.subject.hlbsecondlevelChemical Engineering
dc.subject.hlbsecondlevelPublic Health
dc.subject.hlbsecondlevelBiological Chemistry
dc.subject.hlbsecondlevelChemistry
dc.subject.hlbtoplevelHealth Sciences
dc.subject.hlbtoplevelScience
dc.subject.hlbtoplevelEngineering
dc.description.peerreviewedPeer Reviewed
dc.description.bitstreamurlhttps://deepblue.lib.umich.edu/bitstream/2027.42/143596/1/cpnc1109.pdf
dc.identifier.doi10.1002/0471142700.nc1109s09
dc.identifier.sourceCurrent Protocols in Nucleic Acid Chemistry
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dc.owningcollnameInterdisciplinary and Peer-Reviewed


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