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Solid‐Phase Supports for Oligonucleotide Synthesis
dc.contributor.authorPon, Richard T.
dc.date.accessioned2018-05-15T20:12:48Z
dc.date.available2018-05-15T20:12:48Z
dc.date.issued2000-02
dc.identifier.citationPon, Richard T. (2000). "Solid‐Phase Supports for Oligonucleotide Synthesis." Current Protocols in Nucleic Acid Chemistry 00(1): 3.1.1-3.1.28.
dc.identifier.issn1934-9270
dc.identifier.issn1934-9289
dc.identifier.urihttps://hdl.handle.net/2027.42/143613
dc.description.abstractThis unit begins with a discussion of the advantages and disadvantages of oligonucleotide synthesis using solid supports. The physical and chemical properties of solid‐phase supports are discussed in terms of their suitability for oligonucleotide synthesis. In addition, the unit outlines the properties of linkers used for transient or permanent attachment of properly protected nucleosides to the derivatized support, as well as strategies for coupling nucleosides to linkers and conditions for the release of synthetic oligonucleotides from specific supports.
dc.publisherWiley Periodicals, Inc.
dc.publisherElsevier Science Publishing
dc.titleSolid‐Phase Supports for Oligonucleotide Synthesis
dc.typeArticleen_US
dc.rights.robotsIndexNoFollow
dc.subject.hlbsecondlevelPublic Health
dc.subject.hlbsecondlevelBiological Chemistry
dc.subject.hlbsecondlevelChemical Engineering
dc.subject.hlbsecondlevelChemistry
dc.subject.hlbtoplevelHealth Sciences
dc.subject.hlbtoplevelScience
dc.subject.hlbtoplevelEngineering
dc.description.peerreviewedPeer Reviewed
dc.description.bitstreamurlhttps://deepblue.lib.umich.edu/bitstream/2027.42/143613/1/cpnc0301.pdf
dc.identifier.doi10.1002/0471142700.nc0301s00
dc.identifier.sourceCurrent Protocols in Nucleic Acid Chemistry
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