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Preparation of Gold Nanoparticle–DNA Conjugates
dc.contributor.authorTaton, T. Andrew
dc.date.accessioned2018-05-15T20:13:39Z
dc.date.available2018-05-15T20:13:39Z
dc.date.issued2002-06
dc.identifier.citationTaton, T. Andrew (2002). "Preparation of Gold Nanoparticle–DNA Conjugates." Current Protocols in Nucleic Acid Chemistry 9(1): 12.2.1-12.2.12.
dc.identifier.issn1934-9270
dc.identifier.issn1934-9289
dc.identifier.urihttps://hdl.handle.net/2027.42/143655
dc.description.abstractThis unit describes the preparation of conjugates between nanometer‐scale gold particles and synthetic oligonucleotides. Oligonucleotide‐functionalized gold nanoparticles are finding increased use in both the construction of complex, tailored nanostructures and the optimization of DNA sequence analysis. The protocols in this unit outline the synthesis, purification, and characterization of nanoparticle‐DNA conjugates for applications in nanotechnology and biotechnology. Separate procedures are presented for nanoparticles functionalized with just one or a few oligonucleotide strands and for nanoparticles functionalized with a dense layer of oligonucleotide strands. The different physical and chemical properties of these two types of conjugates are discussed, as are their stability and utility in different environments.
dc.publisherWiley Periodicals, Inc.
dc.titlePreparation of Gold Nanoparticle–DNA Conjugates
dc.typeArticleen_US
dc.rights.robotsIndexNoFollow
dc.subject.hlbsecondlevelChemistry
dc.subject.hlbsecondlevelPublic Health
dc.subject.hlbsecondlevelBiological Chemistry
dc.subject.hlbsecondlevelChemical Engineering
dc.subject.hlbtoplevelHealth Sciences
dc.subject.hlbtoplevelScience
dc.subject.hlbtoplevelEngineering
dc.description.peerreviewedPeer Reviewed
dc.description.bitstreamurlhttps://deepblue.lib.umich.edu/bitstream/2027.42/143655/1/cpnc1202.pdf
dc.identifier.doi10.1002/0471142700.nc1202s09
dc.identifier.sourceCurrent Protocols in Nucleic Acid Chemistry
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dc.owningcollnameInterdisciplinary and Peer-Reviewed


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