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Enzymatic Synthesis of M1Gâ Deoxyribose
dc.contributor.authorSchnetz‐boutaud, Nathalie C.
dc.contributor.authorChapeau, Marie‐christine
dc.contributor.authorMarnett, Lawrence J.
dc.date.accessioned2018-05-15T20:14:04Z
dc.date.available2018-05-15T20:14:04Z
dc.date.issued2000-02
dc.identifier.citationSchnetz‐boutaud, Nathalie C. ; Chapeau, Marie‐christine ; Marnett, Lawrence J. (2000). "Enzymatic Synthesis of M1Gâ Deoxyribose." Current Protocols in Nucleic Acid Chemistry 00(1): 1.2.1-1.2.8.
dc.identifier.issn1934-9270
dc.identifier.issn1934-9289
dc.identifier.urihttps://hdl.handle.net/2027.42/143678
dc.description.abstractAdducts formed between electrophiles and nucleic acid bases are believed to play a key role in chemically induced mutations and cancer. M1Gâ dR is an endogenous exocyclic DNA adduct formed by the reaction of the dicarbonyl compound malondialdehyde with a dG residue in DNA. It is an intermediate in the synthesis of a class of modified oligodeoxyribonucleotides that are used to study the mutagenicity and repair of M1G. This unit presents methods for synthesizing M1Gâ dR by enzymatic coupling.
dc.publisherPlenum
dc.publisherWiley Periodicals, Inc.
dc.titleEnzymatic Synthesis of M1Gâ Deoxyribose
dc.typeArticleen_US
dc.rights.robotsIndexNoFollow
dc.subject.hlbsecondlevelBiological Chemistry
dc.subject.hlbsecondlevelChemical Engineering
dc.subject.hlbsecondlevelPublic Health
dc.subject.hlbsecondlevelChemistry
dc.subject.hlbtoplevelHealth Sciences
dc.subject.hlbtoplevelScience
dc.subject.hlbtoplevelEngineering
dc.description.peerreviewedPeer Reviewed
dc.description.bitstreamurlhttps://deepblue.lib.umich.edu/bitstream/2027.42/143678/1/cpnc0102.pdf
dc.identifier.doi10.1002/0471142700.nc0102s00
dc.identifier.sourceCurrent Protocols in Nucleic Acid Chemistry
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dc.owningcollnameInterdisciplinary and Peer-Reviewed


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