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Protection of 2′‐Hydroxy Functions of Ribonucleosides
dc.contributor.authorReese, Colin B.
dc.date.accessioned2018-05-15T20:14:59Z
dc.date.available2018-05-15T20:14:59Z
dc.date.issued2000-02
dc.identifier.citationReese, Colin B. (2000). "Protection of 2′‐Hydroxy Functions of Ribonucleosides." Current Protocols in Nucleic Acid Chemistry 00(1): 2.2.1-2.2.24.
dc.identifier.issn1934-9270
dc.identifier.issn1934-9289
dc.identifier.urihttps://hdl.handle.net/2027.42/143728
dc.description.abstractThe main purpose of this article is to discuss 2′‐protection in the context of effective oligoribonucleotide synthesis. Emphasis is placed on the 2′‐protecting groups of choice in the synthesis of oligo‐and polyribonucleotides, and the requirements that a protective group must satisfy to become the 2′‐hydroxyl‐protecting group of choice. Finally, the unit discusses the issue of 2′‐O‐acyl and 2′‐O‐silyl group migration to the 3′‐hydroxy function of ribonucleosides during protection, along with the consequences of the conditions used for their removal on the stability of internucleotide linkages.
dc.publisherOxford University Press
dc.publisherWiley Periodicals, Inc.
dc.titleProtection of 2′‐Hydroxy Functions of Ribonucleosides
dc.typeArticleen_US
dc.rights.robotsIndexNoFollow
dc.subject.hlbsecondlevelBiological Chemistry
dc.subject.hlbsecondlevelChemical Engineering
dc.subject.hlbsecondlevelChemistry
dc.subject.hlbsecondlevelPublic Health
dc.subject.hlbtoplevelScience
dc.subject.hlbtoplevelHealth Sciences
dc.subject.hlbtoplevelEngineering
dc.description.peerreviewedPeer Reviewed
dc.description.bitstreamurlhttps://deepblue.lib.umich.edu/bitstream/2027.42/143728/1/cpnc0202.pdf
dc.identifier.doi10.1002/0471142700.nc0202s00
dc.identifier.sourceCurrent Protocols in Nucleic Acid Chemistry
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Remediation of Harmful Language

The University of Michigan Library aims to describe library materials in a way that respects the people and communities who create, use, and are represented in our collections. Report harmful or offensive language in catalog records, finding aids, or elsewhere in our collections anonymously through our metadata feedback form. More information at Remediation of Harmful Language.

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